THE RESPONSE OF T CELLS TO HISTOCOMPATIBILITY-2 ANTIGENS [PDF]
Richard K. Gershon, Stephen A. Liebhaber
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New anticancer therapies with potential cardiovascular side effects are continuously being introduced into clinical practice, with new and often unexpected toxicities becoming apparent only after clinical introduction. These unknown toxicities should be identified and understood beforehand to better prepare patients and physicians, enabling the ...
Alessandra Ghigo+22 more
wiley +1 more source
Cooperation across the histocompatibility barrier: H2d T cells primed to antigen in an H-2d environment can cooperate with H-2k B cells. [PDF]
Herman Waldmann+2 more
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Major histocompatibility complex products restrict the adherence of cytolytic T lymphocytes to minor histocompatibility antigens or to trinitrophenyl determinants on schistosomula of Schistosoma mansoni. [PDF]
Mathew A. Vadas+3 more
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The transcription factor RIP140 regulates interferon γ signaling in breast cancer
What's new? Interferon γ (IFNγ) is a key player in breast cancer, with the potential to induce apoptosis and to shift tumors into a dormant state. However, it also may promote carcinogenesis and angiogenesis. In this study, transcriptomic analysis identified the transcription factor RIP140 as a key regulator of IFNγ signaling in breast cancer.
Stéphan Jalaguier+9 more
wiley +1 more source
What's new? Novel immunomodulatory insights derived from experimental models and clinical samples reveal the cancer‐preventive potential of intermittent low‐dose erlotinib plus sulindac (ERL + SUL). This study shows that ERL + SUL treatment upregulates MHC class I and II expression and remodels the immune cell niche, with significant tumor suppression ...
Chakrapani Tripathi+17 more
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GUINEA PIG HISTOCOMPATIBILITY ANTIGENS I. SEROLOGICAL AND GENETIC CHARACTERIZATION OF GPLA ANTIGENS
A.L. de Weck+3 more
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Engineered strategies for the allergic disease therapy
Allergic diseases exist widely across the globe and now there are very limited therapeutics for the treatment of these diseases. In this review, we summarize the recent advances in engineering strategies including nanoemulsion and hydrogel to improve the therapeutic efficacy of allergen‐specific immunotherapy with decreased side effects and long‐term ...
Yun Tian+4 more
wiley +1 more source
Minor histocompatibility antigens and the maternal immune response to the fetus during pregnancy. [PDF]
Linscheid C, Petroff MG.
europepmc +1 more source