Results 201 to 210 of about 150,657 (357)

Update on preclinical models of cancer therapy‐related cardiac dysfunction: Challenges and perspectives. A scientific statement of the Heart Failure Association (HFA) of the ESC, the ESC Council of Cardio‐Oncology, and the ESC Working Group on Cellular Biology of the Heart

open access: yesEuropean Journal of Heart Failure, EarlyView.
New anticancer therapies with potential cardiovascular side effects are continuously being introduced into clinical practice, with new and often unexpected toxicities becoming apparent only after clinical introduction. These unknown toxicities should be identified and understood beforehand to better prepare patients and physicians, enabling the ...
Alessandra Ghigo   +22 more
wiley   +1 more source

The transcription factor RIP140 regulates interferon γ signaling in breast cancer

open access: yesInternational Journal of Cancer, Volume 157, Issue 1, Page 170-182, 1 July 2025.
What's new? Interferon γ (IFNγ) is a key player in breast cancer, with the potential to induce apoptosis and to shift tumors into a dormant state. However, it also may promote carcinogenesis and angiogenesis. In this study, transcriptomic analysis identified the transcription factor RIP140 as a key regulator of IFNγ signaling in breast cancer.
Stéphan Jalaguier   +9 more
wiley   +1 more source

Antitumor efficacy of intermittent low‐dose erlotinib plus sulindac via MHC upregulation and remodeling of the immune cell niche

open access: yesInternational Journal of Cancer, Volume 157, Issue 2, Page 355-370, 15 July 2025.
What's new? Novel immunomodulatory insights derived from experimental models and clinical samples reveal the cancer‐preventive potential of intermittent low‐dose erlotinib plus sulindac (ERL + SUL). This study shows that ERL + SUL treatment upregulates MHC class I and II expression and remodels the immune cell niche, with significant tumor suppression ...
Chakrapani Tripathi   +17 more
wiley   +1 more source

Engineered strategies for the allergic disease therapy

open access: yesInterdisciplinary Medicine, EarlyView.
Allergic diseases exist widely across the globe and now there are very limited therapeutics for the treatment of these diseases. In this review, we summarize the recent advances in engineering strategies including nanoemulsion and hydrogel to improve the therapeutic efficacy of allergen‐specific immunotherapy with decreased side effects and long‐term ...
Yun Tian   +4 more
wiley   +1 more source

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