Recommendations From the Implementation Steering Group for Organ Utilisation Histocompatibility and Immunogenetics Sub-Group: ISOU H&I Sub-Group Recommendations. [PDF]
Speirs NC +14 more
europepmc +1 more source
Single‐cell and spatial profiling reveal that lymphovascular space invasion in endometrioid endometrial carcinoma is driven by coordinated interactions among metastatic epithelium, fibroblasts, immune cells, and endothelium. This multicellular network promotes matrix remodelling, angiogenesis, and immune evasion, forming a pro‐metastatic niche that ...
Wendi Guo +7 more
wiley +1 more source
Identification of the Novel HLA-C*03:536:02 Allele in a Chinese Cord Blood Donor. [PDF]
Dong L, Wang F, Li Q, He Y, Zhu F.
europepmc +1 more source
Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini +4 more
wiley +1 more source
The Novel HLA-C*01:303 Allele, Identified in a Living Liver Donor of Canadian Dutch Descendent. [PDF]
Sidahmed AME +4 more
europepmc +1 more source
CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén +11 more
wiley +1 more source
Skewed MHC Class I Peptide Presentation in Psoriatic Arthritis. [PDF]
Comdühr S +11 more
europepmc +1 more source
The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma
(Left)The identification and elimination of tumour cells is enabled by the infiltration of functional innate and adaptive immune effectors into the TME, such as natural killer cells (NK cells) and cytotoxic T cells (CD8 T cells). Effective innate and adaptive immune responses facilitate immunological control of malignant outgrowth.
Sarah J. MacDonald +6 more
wiley +1 more source
Vaccine Therapy for the Management of Penile Cancer: Evidence, Opportunities and Challenges. [PDF]
Hatoum F +7 more
europepmc +1 more source
Tissue Resident Memory Cells: Friend or Foe?
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source

