Results 231 to 240 of about 287,914 (297)

Identification of Seven Novel HLA Alleles by Third Generation Sequencing. [PDF]

HLA
Sutherland AH, Turner TR, Flaxl LM, Swadling L, Mayor NP.   +4 more
europepmc   +1 more source

Aire and Fezf2 Shape the Medullary Thymic Epithelial Cell Immunopeptidome for Central Tolerance

Immunology, EarlyView.
Central tolerance is shaped not merely by promiscuous gene expression in medullary thymic epithelial cells (mTECs), but by the subset of self‐peptides ultimately presented on MHC class II molecules. We propose a multilayered framework in which AIRE/Aire and FEZF2/Fezf2, together with specialised differentiation programmes—including thymic mimetic‐cell ...
Geraldo Aleixo Passos, Vitor Marcel Faça, Eduardo Antonio Donadi, Ana Paula Masson, Carlos Crippa Coletto, Gustavo Ronconi Roza   +5 more
wiley   +1 more source

Genomic and proteomic insights into hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology, EarlyView.
A dual pathogenic model of HS involving both epithelial dysfunction and systemic inflammation is supported. The HLA‐DRA association hints at autoimmune overlap, but the proteomic signature which is dominated by innate immune mediators favours an autoinflammatory classification, which may guide future therapeutic strategies and patient stratification ...
Maria Argyropoulou, Emmanouil Stylianakis, Isis Ricaño‐Ponce, Nick Keur, Theodora Kanni, Dimitra Stergianou, Mihai G. Netea, Vinod Kumar, Evangelos J. Giamarellos‐Bourboulis   +8 more
wiley   +1 more source

Highlight of 2025: From binding prediction to molecular design-computational advances in TCR-pMHC prediction and targeting. [PDF]

Immunol Cell Biol
Maire KJ, Coquet JM.
europepmc   +1 more source

Identification of Two Novel HLA-C Alleles, HLA-C*01:284 and HLA-C*01:296. [PDF]

HLA
Li Q, Li Y, Dong L, Zhang W, Zhu F.
europepmc   +1 more source

CLDN18.2 antibody design with protein language models: A deep learning optimization framework. [PDF]

PLoS Comput Biol
Qu T, Yuan L, Cui W, Tang J, Bing Z, Xu X, Duan J, Yang Q, Cai H.   +8 more
europepmc   +1 more source

Development and clinical implementation of a local automated kidney allocation platform integrating virtual crossmatch. [PDF]

Front Immunol
Awaji M, AlZahrani S, Bamrdouf R, AlAbduladheem D, Mohammed A, Alzahrani M, Alkebasi S, Alshallali BM, Alreaan AS, Bosbait SM, Askandarani S, Musaied NA, Akkari KB, AlQahtani M, Alabadi AM.   +14 more
europepmc   +1 more source

The Phenotype List String Grammar for Enhanced Protein and Antigen Reporting in the Immunogenetic Context. [PDF]

HLA
Mack SJ, Brown NK, Gragert L, Hofmann JA, Lemieux W, Matern BM, Osoegawa K, Sauter J, Maiers M, Spierings E.   +9 more
europepmc   +1 more source

Minor histocompatibility antigens

Current Opinion in Immunology, 1997
The existence of transplantation antigens, in addition to those encoded by genes in the MHC, has been known for over half a century. The molecular identification of these additional minor histocompatibility (H) antigens lagged behind that of their MHC counterparts, largely because minor H antigens are recognised by T cells and not by antibodies. In the
Simpson, E, Roopenian, D C
core   +4 more sources