Mixed Lymphocyte Reaction: Functional Immune Profiling in Transplantation and Beyond. [PDF]
Galimov N +3 more
europepmc +1 more source
Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs +6 more
wiley +1 more source
Status quo of histocompatibility testing and prospects for virtual crossmatching within the Korean kidney allocation system: survey of laboratory directors. [PDF]
Yang JJ +6 more
europepmc +1 more source
Genomic and proteomic insights into hidradenitis suppurativa
A dual pathogenic model of HS involving both epithelial dysfunction and systemic inflammation is supported. The HLA‐DRA association hints at autoimmune overlap, but the proteomic signature which is dominated by innate immune mediators favours an autoinflammatory classification, which may guide future therapeutic strategies and patient stratification ...
Maria Argyropoulou +8 more
wiley +1 more source
Translational potential of γδ T cells in hematologic diseases: from immunobiology to therapeutic innovation. [PDF]
Zhou X, Zhai M, Zhang Z, Zhang G.
europepmc +1 more source
The organ transplanted patient - immunological concepts and immunosuppression [PDF]
Husberg, BS, Klintmalm, GBG, Starzl, TE
core
Abstract Fishes experience thermal stress in their natural environment that can be caused by natural or anthropogenic factors and can directly affect their physiology. In this study, we developed a multispecies OpenArray™ qPCR (quantitative polymerase chain reaction) ‘chip’ to measure the effects of acute thermal stress on the mRNA response of ...
Hossein Haghighi +6 more
wiley +1 more source
Mechanisms of paraneoplastic neurological syndromes. [PDF]
Kunchok A, Vogrig A, Graus F.
europepmc +1 more source
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed +6 more
wiley +1 more source
Correlation between recognition of autologous tumor organoids by tumor-infiltrating lymphocytes from metastatic epithelial cancers and clinical response. [PDF]
Gustafson AM +16 more
europepmc +1 more source

