Results 241 to 250 of about 159,586 (333)

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

Allergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm, Mohammed Zghaebi, Bita Hambrecht, Tanja Kalic, Christopher C. Udoye, Rudolf Manz, Barbara Bohle, Katarzyna M. Sitnik, Julia Eckl‐Dorna, Heimo Breiteneder   +9 more
wiley   +1 more source

A new path to spillover: MHC-II entry of influenza A viruses. [PDF]

PLoS Biol
Stertz S, Karakus U.
europepmc   +1 more source

Effect of Herbal Medicines on Cytokine-Induced Cytotoxicity and Major Histocompatibility Complex (MHC) Class II Antigen Expression in Rat Thyroid Cells

, 2004
Yun‐Hee Shon, Hee-Soon Lee, Cheorl‐Ho Kim, Jong‐Kook Lim, Byung-Hun Jeon, Kyung‐Soo Nam   +5 more
openalex   +2 more sources

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

PepQueryMHC: rapid and comprehensive tumor antigen prioritization from immunopeptidomics data. [PDF]

Genome Biol
Choi S, Zhang B.
europepmc   +1 more source

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

British Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

Lipopeptide ligands captured by MHC class I molecules undergo dynamic conformational changes that affect their antigenic strength. [PDF]

J Biol Chem
Morita D, Fujii T, Inuki S, Suzuki H, Mikami B, Sugita M.   +5 more
europepmc   +1 more source

The organ transplanted patient - immunological concepts and immunosuppression [PDF]

, 1991
Husberg, BS, Klintmalm, GBG, Starzl, TE
core  

Molecular dissection of the antigen binding site of a major histocompatibility complex class II molecule and stochastic modelling of macromolecular interactions in the living cell

, 1991
Jean Peccoud
openalex   +1 more source

A continuous infusion of a minor histocompatibility antigen–immunodominant peptide induces a delay of male skin graft rejection

, 2009
Guido Sireci, Annalisa Barera, Pasquale Macaluso, Caterina Di Sano, Cesira T. Bonanno, Marco Pio La Manna, Diana Di Liberto, Francesco Dieli, Alfredo Salerno   +8 more
openalex   +2 more sources