Results 251 to 260 of about 159,586 (333)

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Non-HLA Genetics and Application to Living Donor Candidates. [PDF]

Curr Transplant Rep
Caliskan Y, Afsar B, Afsar RE, Varma C, Aygormez O, Lentine KL.   +5 more
europepmc   +1 more source

Interaction of Class I major histocompatibility molecules with the transporter associated with antigen processing (TAP) and the molecular chaperone calnexin [PDF]

, 1998
Woong‐Kyung Suh
openalex  

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, EarlyView.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source

Beyond PD‐1: Mechanisms of Resistance to Checkpoint Blockade in Classical Hodgkin Lymphoma and Next‐Generation Immune Strategies

European Journal of Haematology, EarlyView.
ABSTRACT PD‐1 inhibitors have reshaped the treatment landscape of classical Hodgkin lymphoma, yet a substantial proportion of patients exhibit primary or acquired resistance driven by tumor‐intrinsic alterations, immunosuppressive microenvironmental signals, metabolic constraints, and EBV‐mediated modulation.
Santino Caserta, Enrica Antonia Martino, Mamdouh Skafi, Maria Eugenia Alvaro, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Ernesto Vigna, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Biomimetic carbon nanopolymers ANM-NPs act on mannose receptors and complement receptors to promote tumor antigen presentation. [PDF]

J Immunother Cancer
Feng Z, Shi X, Li Z, Lou M, Cui B, Chen M, Zhang L, Sun Y, Zhang H, Li YN, Liu H, Sun T.   +11 more
europepmc   +1 more source

Milestones in Transplantation: The Story so Far [PDF]

, 2001
Starzl, TE
core  

Crucial Role For Cross-Presentation In The Induction Of GVHD By T Cells Directed Against A Single Immunodominant Minor Histocompatibility Antigen Despite Lack Of Epitope Spreading

, 2010
Tomomi Toubai, Isao Tawara, Chelsea Malter, Polly Matzinger, Pavan Reddy   +4 more
openalex   +1 more source

Artificial lipidation of proteins and peptides: from mechanism to clinical applications

The FEBS Journal, EarlyView.
Artificial lipidation transforms protein and peptide therapeutics by attaching fatty acid chains through reversible or permanent chemical strategies. This biomimetic approach delivers four key therapeutic advantages: extended circulation times (enabling weekly instead of daily dosing), alternative administration routes including oral delivery, precise ...
Jiaming Mu, Emily Vong, Sheiliza Carmali
wiley   +1 more source

Decoding the Cryptic Proteome Between Antigens and Novel Functional Proteins. [PDF]

Eur J Immunol
Bawden EG, Amigorena S, Arribas YA.
europepmc   +1 more source