Results 211 to 220 of about 112,304 (310)

Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs   +6 more
wiley   +1 more source

Anti-HLA antibodies in lung transplantation: diagnostic pitfalls and future directions. [PDF]

open access: yesEur Respir Rev
Zajacova A   +8 more
europepmc   +1 more source

Genomic and proteomic insights into hidradenitis suppurativa

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
A dual pathogenic model of HS involving both epithelial dysfunction and systemic inflammation is supported. The HLA‐DRA association hints at autoimmune overlap, but the proteomic signature which is dominated by innate immune mediators favours an autoinflammatory classification, which may guide future therapeutic strategies and patient stratification ...
Maria Argyropoulou   +8 more
wiley   +1 more source

Preformed <i>vs de novo</i> anti-human leukocyte antigens-DQ antibodies in kidney transplantation: A retrospective study. [PDF]

open access: yesWorld J Transplant
Guissouss O   +9 more
europepmc   +1 more source

High‐throughput multispecies quantitative polymerase chain reaction assays to study the effects of acute thermal stress in three species of Acipenser sturgeon

open access: yesJournal of Fish Biology, EarlyView.
Abstract Fishes experience thermal stress in their natural environment that can be caused by natural or anthropogenic factors and can directly affect their physiology. In this study, we developed a multispecies OpenArray™ qPCR (quantitative polymerase chain reaction) ‘chip’ to measure the effects of acute thermal stress on the mRNA response of ...
Hossein Haghighi   +6 more
wiley   +1 more source

Recent improvement in clinical pancreas transplantation [PDF]

open access: yes, 1987
Abendroth, D.   +4 more
core   +1 more source

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