Results 201 to 210 of about 112,304 (310)

The use of MHC class I or class II 'knock out' mice to investigate the role of these antigens in allosensitization [PDF]

, 1995
Demetris, AJ, Fu, F, Fung, JJ, Gao, L, Li, Y, Lu, L, Noyola, H, Qian, S, Rao, AS, Starzl, TE, Thomson, AW   +10 more
core  

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Selection and Characterisation of Minor Histocompatibility Antigen-Specific Regulatory T Cells in Fully HLA-Matched Setting for GVHD Therapy. [PDF]

Eur J Immunol
Pacini CP, Azevedo RI, Ramalhete L, Lainé HAJ, Soares MVD, Lacerda JF.   +5 more
europepmc   +1 more source

TNF‑α Gene Polymorphisms as Determinants of Alloantibody Emergence in Hemophilia: A Systematic Review and Meta‐Analysis

Haemophilia, EarlyView.
ABSTRACT Introduction Inhibitor development remains one of the most serious complications of replacement therapy in patients with hemophilia. Tumour necrosis factor‐alpha (TNF‐α) is a key pro‐inflammatory cytokine, and its genetic variants have been implicated in immune‐related conditions.
Alessandra Faustino da Conceição Bezerra, Natã Abner Andrade Carito de Sousa, Suely Meireles Rezende, Renan Pedra de Souza   +3 more
wiley   +1 more source

Clustering-based identification of immune-related gene signatures in hepatocellular carcinoma. [PDF]

Ecancermedicalscience
Brahmaiah J, Adiga U, Augustine AJ, Vasishta S.   +3 more
europepmc   +1 more source

HLA Class I Histocompatibility Antigen, A-1 Alpha Chain [PDF]

, 2020
openaire   +1 more source

Cytosolic delivery of bacterial metabolites by riboflavin transporters promotes MR1 antigen presentation and MAIT cell recognition

Immunology &Cell Biology, EarlyView.
VitBAg antigen presentation is promoted through a cytosolic pathway that reaches ligand‐receptive MR1 to present to MAIT cells, like the riboflavin transport pathway. Riboflavin solute carrier transporters can promote this MR1 presentation, but they are not essential for this role, suggesting redundant pathways to uptake VitBAg.
Sebastian Cruz‐Gomez, Hui Jing Lim, Brunda Nijagal, Yuting Yang, Nicole Lau, Jeffrey YW Mak, David P Fairlie, Hayley Newton, Mariolina Salio, Jose A Villadangos, Hamish EG McWilliam   +10 more
wiley   +1 more source

HLA-A*02:1227 and HLA-A*36:16N, Two Novel HLA-A Alleles Identified in Brazilian Bone Marrow Donors. [PDF]

HLA
Dos Santos Júnior ACS, de Oliveira CKF, Fabreti-Oliveira RA.   +2 more
europepmc   +1 more source

HLA Class I Histocompatibility Antigen, A-24 Alpha Chain [PDF]

, 2020
openaire   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source