Results 201 to 210 of about 68,749 (310)

Autophagy Inhibition by Fangji Huangqi Decoction Enhances Tumor Immunogenicity and Potentiates PD‐1 Blockade

Cancer Science, EarlyView.
In tumor cells, MHC‐I is typically degraded through autophagy, leading to reduced antigen presentation. However, Fangji Huangqi Decoction (FJHQ), acting as an autophagy inhibitor, suppresses lysosomal acidification, which in turn inhibits the degradation of MHC‐I. This results in increased surface expression of MHC‐I on tumor cells.
Yuxiao Jiang, Shiji Zeng, Dingye Wang, Junbo Jiang, Zhenzhen Li, Jingbi Li, Dan Chen, Xu Zhao, Zheng Ying, Yuehua Deng, Qianwei Cai, Silin Mai, Jiayi Zheng, Qiaohong Yang, Fang Liu, Biaoyan Du, Jianyong Xiao, Xiaoyi Liu, Kun Wang   +18 more
wiley   +1 more source

Detection of Major Histocompatibility Complex Class I Antigens on the Surface of a Single Murine Blastocyst by Immuno-PCR

BioTechniques, 1997
Abigail S. McElhinny, Carol M. Warner
doaj   +1 more source

Characterisation of tumor-infiltrating gamma-delta T cells in human colorectal cancer with MHC-I loss. [PDF]

Clin Transl Immunology
Li TA, Quigley LT, Chan KF, Williams DS, Mielke LA, Behren A, Da Gama Duarte J.   +6 more
europepmc   +1 more source

Organization of the AKR Qa region [PDF]

, 1989
Steinmetz, M., Grosshaus, C., Messer, Gerald, Schwemmle, Sabine, Schmidt, Walter, Bevec, Dorian, Weiss, Elisabeth H.   +6 more
core   +1 more source

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, EarlyView.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source

Association Between Baseline Anti-HLA (Class I and II) and Anti-MICA Antibodies and Inflammatory Cell Infiltrates in Grafted Bone After Maxillary Sinus Floor Augmentation: An Exploratory Secondary Histological Study. [PDF]

Life (Basel)
Dominiak S, Dominiak M, Hadzik J, Ciszyński M, Kepinska M, Banasik M, Piotrowska A, Dzięgiel P, Gedrange T, Baranowska A, Kubasiewicz-Ross P.   +10 more
europepmc   +1 more source

HLA Class I Histocompatibility Antigen, Alpha Chain F [PDF]

, 2020
openaire   +1 more source

Single Cell Multi‐Omics Revealing the Important Role of MR1 Mediated MAIT Cells in Maintaining Rejection for Liver Transplantation

Cell Proliferation, EarlyView.
This multi‐omics study reveals the significant role of MAIT cells in liver transplant rejection. MAIT cells drive rejection in liver transplantation via the MR1 axis. Their absence reshapes T cell responses and clonal expansion, attenuating allograft injury.
Hailun Cai, Xinqiang Li, Xin Zhou, Xueteng Wang, Zhuoyu Jia, Ruidong Ding, Yurong Luo, Ye Wang, Shipeng Li, Wenxing Sun, Dongxing Wu, Dahong Teng, Kai Zhao, Guanghui Pei, Jinzhen Cai, Bin Wu   +15 more
wiley   +1 more source

HLA Type and the Effect of HLA Antibodies in Kidney, Liver, and Pancreas Transplantation: A Review. [PDF]

Avicenna J Med Biotechnol
Zarei E, Roozbeh J, Nikoupour Deylami H, Nikeghbalian S, Ahrami M, Nasrollozoda F, Hashemzehi A, Hashemzaei M.   +7 more
europepmc   +1 more source

HLA Class I Histocompatibility Antigen, Alpha Chain G [PDF]

, 2020
openaire   +1 more source