Results 221 to 230 of about 68,749 (310)

Antibody-Dependent Cytotoxicity of Monocytes in Preeclampsia Is Associated with Soluble Forms of HLA. [PDF]

Int J Mol Sci
Krasnyi AM, Sorokina LE, Argentova-Stevens AM, Kokoeva DN, Alekseev AA, Jankevic T, Kan NE, Tyutyunnik VL, Sukhikh GT.   +8 more
europepmc   +1 more source

Post‐Transplant Bendamustine as a Platform for Immune Modulation After Allogeneic Hematopoietic Cell Transplantation

European Journal of Haematology, EarlyView.
ABSTRACT Post‐transplant cyclophosphamide (PT‐CY) remains the standard of care for graft‐versus‐host disease (GvHD) prophylaxis in haploidentical hematopoietic cell transplantation (HCT), yet relapse, delayed immune reconstitution, infections, and organ toxicity represent persistent and clinically meaningful limitations.
Megan J. Cracchiolo, Richard J. Simpson, Emmanuel Katsanis   +2 more
wiley   +1 more source

Computational design of HLA class I superbinders for broad T cell immunogenicity. [PDF]

Proc Natl Acad Sci U S A
Peer E, Cohen-Lavi L, Sette A, Sidney J, Hertz T.   +4 more
europepmc   +1 more source

HLA Class I Histocompatibility Antigen, A-11 Alpha Chain [PDF]

, 2020
openaire   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Non-Classical HLA and MIC Risk Score Is Associated With Acute Kidney Transplant Rejection Beyond Classical HLA Matching. [PDF]

HLA
Tammi S, Markkinen S, Helanterä I, Lempinen M, Partanen J, Hyvärinen K, Ritari J.   +6 more
europepmc   +1 more source

Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response

The FEBS Journal, EarlyView.
Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril, Matthieu Le Gallo, Elodie Lafont   +2 more
wiley   +1 more source

HLA Class I Histocompatibility Antigen, A-2 Alpha Chain [PDF]

, 2020
openaire   +1 more source

Diagnostic utility of inflammatory markers in formalin‐fixed and paraffin‐embedded muscle biopsies for idiopathic inflammatory myopathies

Histopathology, EarlyView.
Formalin‐fixed, paraffin‐embedded (FFPE) muscle tissue supports robust immunohistochemical detection of MHC II, MxA, and p62 with performance comparable to frozen sections. This approach reliably identifies the pathological signatures of inclusion body myositis, dermatomyositis, immune‐mediated necrotizing myopathy, and overlap myositis, enhancing the ...
Chinnawut Suriyonplengsaeng, Jariya Waisayarat   +1 more
wiley   +1 more source

Targeting the pMHC-TCR Interaction: Molecular Strategies and Therapeutic Potential in Autoimmunity. [PDF]

Int J Mol Sci
Nechaeva AM, Mamedov AE, Ovchinnikova LA, Zakharova MY.   +3 more
europepmc   +1 more source