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Characterization of class II histocompatibility antigens in pigs
Animal Blood Groups and Biochemical Genetics, 1981SummaryThe D region of the SLA complex in the pig has been studied by immunochemical and sequential immunoprecipitation techniques as well as the redistribution of membranous antigens (capping). The molecules identified by the anti‐la sera were solubilized by NP 40, purified on lectin and precipitated.
P, Chardon, C, Renard, M, Vaiman
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Interaction of peptide antigens and class II major histocompatibility complex antigens
Nature, 1986T lymphocytes require a foreign antigen to be presented on a cell surface in association with a self-transplantation antigen before they can recognize it effectively. This phenomenon is known as major histocompatibility complex (MHC) restriction. It is not clear how an incalculably large number of foreign proteins form unique complexes with a very ...
J G, Guillet +4 more
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Genetic Complexity and Expression of Human Class II Histocompatibility Antigens
Immunological Reviews, 1985The genes encoding nearly all of the serologically defined class II antigens of the major histocompatibility complex have been isolated. Three class II loci have been studied in great detail. The DR region contains a single alpha gene and 3 beta chain genes, 1 of which is a pseudogene.
A J, Korman +5 more
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Intrathyroidal Mast Cells Express Major Histocompatibility Complex Class-II Antigens
International Archives of Allergy and Immunology, 1989We studied the expression of major histocompatibility complex (MHC) class-II antigen in mast cells of rat thyroid glands. In the normal rat thyroid, mast cells express MHC class-II antigen. In BioBreeding Wistar (BB/W) rats, the strain of animals prone to develop spontaneous autoimmune thyroiditis, the number of MHC class-II-positive mast cells was ...
K, Banovac +4 more
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ALLOSPECIFIC MONOCLONAL ANTIBODIES RECOGNIZING RAT CLASS I AND CLASS II HISTOCOMPATIBILITY ANTIGENS
Transplantation, 1982Rat-mouse hybridomas have been developed producing monoclonal antibodies which recognize rat major histocompatibility complex specificities. Splenic lymphocytes from a LEW (RT1l) rat alloimmunized against ACI (Rt1a) splenocytes were used for hybridoma production.
E E, Engel, R D, Guttmann, A, Fuks
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Journal of Clinical Immunology, 1988
Class II antigens encoded by genes of the major histocompatibility complex (MHC) are expressed by a variety of cell types and have a vital role in the cellular interactions required for an effective immune response. We have analyzed the regulation of HLA-DR, DP, and DQ class II antigen expression on cells of different lineage from an immunodeficient ...
S, Plaeger-Marshall +7 more
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Class II antigens encoded by genes of the major histocompatibility complex (MHC) are expressed by a variety of cell types and have a vital role in the cellular interactions required for an effective immune response. We have analyzed the regulation of HLA-DR, DP, and DQ class II antigen expression on cells of different lineage from an immunodeficient ...
S, Plaeger-Marshall +7 more
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Expression of class I and class II major histocompatibility complex antigens on human hepatocytes
Hepatology, 1988We analyzed whether normal human hepatocytes, which normally do not display Class II major histocompatibility complex antigens, can be induced to express them in vitro, and whether this induction has an in vivo counterpart in chronic liver diseases.
A. Franco +5 more
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Major Histocompatibility Complex Class II Antigen Presentation in Hodgkin's Disease
Leukemia & Lymphoma, 1999The malignant cells in Hodgkin's disease (HD), commonly referred to as Hodgkin and Reed-Sternberg (HRS) cells, express major histocompatibility complex (MHC) class II molecules and, like "professional" antigen-presenting cells (APCs), different accessory or costimulatory molecules which can provide an additional activation signal to T cells.
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