Results 261 to 270 of about 453,877 (390)

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Fully Phased Population-Prevalent East African Cattle BoLA-I Alleles Determined Using PacBio HiFi Long-Read Sequencing Represent Five Novel Specificities With Distinctive Peptide Binding Potential. [PDF]

HLA
Obara I, Sandro A, Elati K, Conneley T, Nielsen M, Githaka N, Nanteza A, Bishop R, Nijhof A.   +8 more
europepmc   +1 more source

The Importance of Particle Shape: Effect of Nonspherical Particles and Their Stabilized Pickering Emulsions on Immunization Efficacy

Small Science, EarlyView.
Poly (lactic‐co‐glycolic acid) is used to prepare nonspherical particles—macrofibers, macrothreads, and nanothreads (PNTs)—via one‐step solvent phase separation. PNT‐stabilized Pickering emulsions exhibit superior humoral and cellular immune enhancement over spherical particles and emulsions, highlighting the potential of nonspherical particles and ...
Yanan Li, Jie Teng, Qiuting Chen, Qingze Fan, Hiroyuki Oku, Guanghui Ma, Jie Wu   +6 more
wiley   +1 more source

Predicting reverse-bound peptide conformations in MHC Class II with PANDORA. [PDF]

Front Immunol
Rademaker DT, Parizi FM, van Vreeswijk M, Eerden S, Marzella DF, Xue LC.   +5 more
europepmc   +1 more source

A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes [PDF]

, 2010
Isamu Z. Hartman, AeRyon Kim, Robert J. Cotter, Kimberly Walter, Sarat K. Dalai, Tatiana Boronina, Wendell P. Griffith, David E. Lanar, Robert Schwenk, Urszula Krzych, Robert N. Cole, Scheherazade Sadegh‐Nasseri   +11 more
openalex   +1 more source

Human Dermal Microvascular Arterial and Venous Blood Endothelial Cells and Their Use in Bioengineered Dermo‐Epidermal Skin Substitutes

Small Methods, EarlyView.
This study unveils a pioneering approach to bioengineering of human skin substitutes with distinct arterial and venous capillaries. Combining single‐cell transcriptomics and 3D hydrogel models, this work reveals unique endothelial marker dynamics in fetal and juvenile skin.
Dominic Rütsche, Monica Nanni, Phil Cheng, Nicolà Caflisch, Aizhan Tastanova, Céline Jenni, Mitchell P. Levesque, Ueli Moehrlen, Agnes S. Klar, Thomas Biedermann   +9 more
wiley   +1 more source

Immunogenicity of chondrocyte sheets: a review. [PDF]

Front Immunol
Li J, Sun H, Guan J, Li B, Jin C, Xie S, Liu Y.   +6 more
europepmc   +1 more source

Relationship between target antigens and major histocompatibility complex (MHC) class II genes in producing two pathogenic antibodies simultaneously [PDF]

, 2010
Labib R. Zakka, Derin B. Keskin, Pedro A. Reche, A. R. Ahmed   +3 more
openalex   +1 more source

Exosome‐Based Theranostic for Gastrointestinal Cancer: Advances in Biomarker Discovery and Therapeutic Engineering

Small Methods, EarlyView.
This review explores the dual roles of exosomes in gastrointestinal (GI) cancers as diagnostic biomarkers and therapeutic agents. It highlights advancements in exosomal miRNAs, lncRNAs, circRNAs, and proteins for cancer detection and prognosis. The study also examines engineering strategies for exosome‐based drug delivery systems, their potential to ...
Mohit J. Mehta, Dongjun Shin, Hyun Sung Park, Jun Su An, Seong Il Lim, Hyun Jin Kim, Seungpyo Hong, Jiyoon Bu   +7 more
wiley   +1 more source

Mechanisms of allorecognition and xenorecognition in transplantation. [PDF]

Clin Transplant Res
Yun IH, Yang J.
europepmc   +1 more source