Results 251 to 260 of about 8,473,299 (309)

Moonlighting ERAP Aminopeptidases in Cancer: Beyond Antigen Processing. [PDF]

Cells
Gragera P, Scaldaferri V, Fruci D.
europepmc   +1 more source

Long-term major histocompatibility complex class I suppression in astronauts and clinical implications. [PDF]

Commun Biol
LeRoy E, Kim J, Ruland H, Schanzer N, Sakharkar A, Innes L, Feinstein Z, Gamboa DZ, Chen R, Arikatla MR, Kurt KC, Crucian BE, Schmidt MA, Mason CE.   +13 more
europepmc   +1 more source

Expression of class I and class II major histocompatibility complex antigens on human hepatocytes

Hepatology, 1988
We analyzed whether normal human hepatocytes, which normally do not display Class II major histocompatibility complex antigens, can be induced to express them in vitro, and whether this induction has an in vivo counterpart in chronic liver diseases.
A. Franco, BARNABA, Vincenzo, Piergiorgio Natali, Clara Balsano, Antonino Musca, Francesco Balsano   +5 more
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Interferon-induced expression of class II major histocompatibility antigens in the major histocompatibility complex (MHC) class II deficiency syndrome

Journal of Clinical Immunology, 1988
Class II antigens encoded by genes of the major histocompatibility complex (MHC) are expressed by a variety of cell types and have a vital role in the cellular interactions required for an effective immune response. We have analyzed the regulation of HLA-DR, DP, and DQ class II antigen expression on cells of different lineage from an immunodeficient ...
Irvin S Chen, S G Quan, Jänis V Giorgi
exaly   +3 more sources

Characterization of class II histocompatibility antigens in pigs

Animal Blood Groups and Biochemical Genetics, 1981
SummaryThe D region of the SLA complex in the pig has been studied by immunochemical and sequential immunoprecipitation techniques as well as the redistribution of membranous antigens (capping). The molecules identified by the anti‐la sera were solubilized by NP 40, purified on lectin and precipitated.
P, Chardon, C, Renard, M, Vaiman
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Interaction of peptide antigens and class II major histocompatibility complex antigens

Nature, 1986
T lymphocytes require a foreign antigen to be presented on a cell surface in association with a self-transplantation antigen before they can recognize it effectively. This phenomenon is known as major histocompatibility complex (MHC) restriction. It is not clear how an incalculably large number of foreign proteins form unique complexes with a very ...
J G, Guillet, M Z, Lai, T J, Briner, J A, Smith, M L, Gefter   +4 more
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Structural studies of the class II histocompatibility antigens of the ACI rat

Canadian Journal of Biochemistry and Cell Biology, 1985
The class II antigens of the ACI rat were studied using both conventional alloantisera and monoclonal antibodies. By sequential immunoprecipitation experiments and cell binding studies, alloantisera were shown to contain antibodies to both the RT1.B and the RT1.D gene products.
A J, Goldner-Sauvé, A, Fuks, R D, Guttmann   +2 more
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Genetic Complexity and Expression of Human Class II Histocompatibility Antigens

Immunological Reviews, 1985
The genes encoding nearly all of the serologically defined class II antigens of the major histocompatibility complex have been isolated. Three class II loci have been studied in great detail. The DR region contains a single alpha gene and 3 beta chain genes, 1 of which is a pseudogene.
A J, Korman, J M, Boss, T, Spies, R, Sorrentino, K, Okada, J L, Strominger   +5 more
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Unaltered class II histocompatibility antigens and pathogenesis of IDDM in BB rats

Diabetes, 1989
The BB rat spontaneously develops insulin-dependent diabetes mellitus (IDDM) as an autoimmune abnormality involving the class II molecules of the major histocompatibility complex (MHC). The rat MHC (RT1 complex) encodes two class II loci, RT1 .B and RT1.D.
E W, Holowachuk, M K, Greer
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