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Human Leukocyte Antigen (HLA) and Tumor Immunity: A Critical Link in Cancer Immunotherapy. [PDF]
Damian D.
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Comprehensive mapping of human CD4<sup>+</sup> T cell epitopes for Nipah and measles as prototype Paramyxoviruses. [PDF]
Tarke A +20 more
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Selection and Characterisation of Minor Histocompatibility Antigen-Specific Regulatory T Cells in Fully HLA-Matched Setting for GVHD Therapy. [PDF]
Pacini CP +5 more
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Expression of class I and class II major histocompatibility complex antigens on human hepatocytes
We analyzed whether normal human hepatocytes, which normally do not display Class II major histocompatibility complex antigens, can be induced to express them in vitro, and whether this induction has an in vivo counterpart in chronic liver diseases.
A. Franco +5 more
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Journal of Clinical Immunology, 1988
Class II antigens encoded by genes of the major histocompatibility complex (MHC) are expressed by a variety of cell types and have a vital role in the cellular interactions required for an effective immune response. We have analyzed the regulation of HLA-DR, DP, and DQ class II antigen expression on cells of different lineage from an immunodeficient ...
Loran T Clement +2 more
exaly +3 more sources
Class II antigens encoded by genes of the major histocompatibility complex (MHC) are expressed by a variety of cell types and have a vital role in the cellular interactions required for an effective immune response. We have analyzed the regulation of HLA-DR, DP, and DQ class II antigen expression on cells of different lineage from an immunodeficient ...
Loran T Clement +2 more
exaly +3 more sources
Major histocompatibility complex (MHC) class I and II molecules can both present cytosolic and nuclear antigens to CD8(+) and CD4(+) T cells, respectively. However, MHC class I displays proteasomal, whereas MHC class II molecules display lysosomal, degradation products. One pathway by which intracellular antigens gain access to lysosomal degradation is
Gannagé, M, Münz, C
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Characterization of class II histocompatibility antigens in pigs
Animal Blood Groups and Biochemical Genetics, 1981SummaryThe D region of the SLA complex in the pig has been studied by immunochemical and sequential immunoprecipitation techniques as well as the redistribution of membranous antigens (capping). The molecules identified by the anti‐la sera were solubilized by NP 40, purified on lectin and precipitated.
P, Chardon, C, Renard, M, Vaiman
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Interaction of peptide antigens and class II major histocompatibility complex antigens
Nature, 1986T lymphocytes require a foreign antigen to be presented on a cell surface in association with a self-transplantation antigen before they can recognize it effectively. This phenomenon is known as major histocompatibility complex (MHC) restriction. It is not clear how an incalculably large number of foreign proteins form unique complexes with a very ...
J G, Guillet +4 more
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