Results 271 to 280 of about 108,384 (342)

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi   +10 more
wiley   +1 more source

A Combinatorial Effect of Immune Checkpoint Inhibitors and CD40 Agonistic Antibody in Murine Pancreatic Cancer Model

open access: yesCancer Science, EarlyView.
We established and extensively analyzed an organoid‐based mouse model that closely mimics human pancreatic ductal adenocarcinoma. Monotherapy with an immune checkpoint inhibitor cocktail or a CD40 agonist antibody showed minimal efficacy. However, combining both reagents produced a strong synergistic effect by enhancing anti‐tumor immunity.
Juri Ichikawa   +12 more
wiley   +1 more source

CAR T cell therapy in type 1 diabetes: what we know and what remains to be explored. [PDF]

open access: yesBiol Proced Online
Pattanaik SK   +3 more
europepmc   +1 more source

Major histocompatibility complex class II antigen expression during potentiation of line-10 tumor immunity after intralesional administration of bacillus Calmette-Guérin

open access: green, 1990
Peter A. Steerenberg   +10 more
openalex   +2 more sources

Tumor Microenvironments in Malignant Ovarian Germ Cell Tumors: MHC Class I Loss and T‐Cell Exhaustion in Dysgerminoma

open access: yesCancer Science, EarlyView.
Malignant ovarian germ cell tumor subtypes exhibit distinct tumor microenvironments. Dysgerminomas harbor abundant nonexhausted T cells, with progenitor exhausted T cells present in 60% of PD‐1–positive cases. However, MHC class I expression is lost across all analyzed subtypes, suggesting that restoring class I expression in dysgerminomas may enhance ...
Miya Nakashima   +13 more
wiley   +1 more source

Shaping the Immune Response: Cathepsins in Virus-Dendritic Cell Interactions. [PDF]

open access: yesCells
Niedzielska A   +5 more
europepmc   +1 more source

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