Four Target Resequencing for the Bovine Major Histocompatibility Complex Region. Proof of Concept. [PDF]
HLAGiovambattista G +7 more
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Predicted Indirectly Recognizable T-cell Epitope (PIRCHE) Load Correlates With Rejection Events After Simultaneous Pancreas-Kidney Transplantation. [PDF]
Transplant DirectParajuli S +7 more
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Genetic Complexity and Expression of Human Class II Histocompatibility Antigens
Immunological Reviews, 1985The genes encoding nearly all of the serologically defined class II antigens of the major histocompatibility complex have been isolated. Three class II loci have been studied in great detail. The DR region contains a single alpha gene and 3 beta chain genes, 1 of which is a pseudogene.
Rosa Sorrentino +5 more
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Transplantation, 1986 The expression of monomorphic determinants of class I and class II histocompatibility antigens in human heart before and after cardiac transplantation was examined using monoclonal antibodies and an immunoperoxidase technique. Thirty-five biopsy specimens were examined.
Marlene L. Rose +4 more
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Expression of class I and class II major histocompatibility complex antigens on human hepatocytes
Hepatology, 1988We analyzed whether normal human hepatocytes, which normally do not display Class II major histocompatibility complex antigens, can be induced to express them in vitro, and whether this induction has an in vivo counterpart in chronic liver diseases.
A. Franco +5 more
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Genetic aspects of sarcoidosis. Class II histocompatibility antigens and a family study.
Archives of internal medicine, 1987In a study designed to evaluate the concept of inherited susceptibility to sarcoidosis, 73 patients with histologically proved chronic disease of sarcoid lung fibrosis (group 1) underwent typing of HLA-A, -B, -C and -DR antigens. Tests on 156 antiserum samples comprising 52 antigens of A, B, and C loci and on 35 comprising seven DR antigens on the ...
Dagmar Nowack, Klaus M. Goebel
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Primary biliary cirrhosis: Associations with class II major histocompatibility complex antigens
Hepatology, 1987 Tissue injury in primary biliary cirrhosis is thought to be mediated by immune mechanisms. Various Class II antigens of the major histocompatibility complex are associated with autoimmune diseases and their differing clinical manifestations.
Gregory J. Gores +4 more
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The expression of the Class I and Class II major histocompatibility antigens on oral mucosa was investigated using type‐specific monoclonal antibodies. Class I antigen expression varied between various sites and in uncomplicated inflammatory responses appeared to be suppressed.
Savage, NW, Walsh, LJ, Seymour, GJ
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Interaction of peptide antigens and class II major histocompatibility complex antigens [PDF]
Nature, 1986 T lymphocytes require a foreign antigen to be presented on a cell surface in association with a self-transplantation antigen before they can recognize it effectively. This phenomenon is known as major histocompatibility complex (MHC) restriction. It is not clear how an incalculably large number of foreign proteins form unique complexes with a very ...
Malcolm L. Gefter +4 more
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Unaltered class II histocompatibility antigens and pathogenesis of IDDM in BB rats [PDF]
Diabetes, 1989 The BB rat spontaneously develops insulin-dependent diabetes mellitus (IDDM) as an autoimmune abnormality involving the class II molecules of the major histocompatibility complex (MHC). The rat MHC (RT1 complex) encodes two class II loci, RT1 .B and RT1.D.
Mary K Greer, Eugene W. Holowachuk
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