Results 351 to 360 of about 453,877 (390)
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Characterization of class II histocompatibility antigens in pigs
Animal Blood Groups and Biochemical Genetics, 1981SummaryThe D region of the SLA complex in the pig has been studied by immunochemical and sequential immunoprecipitation techniques as well as the redistribution of membranous antigens (capping). The molecules identified by the anti‐la sera were solubilized by NP 40, purified on lectin and precipitated.
Marcel Vaiman +2 more
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Structural studies of the class II histocompatibility antigens of the ACI rat
Canadian Journal of Biochemistry and Cell Biology, 1985The class II antigens of the ACI rat were studied using both conventional alloantisera and monoclonal antibodies. By sequential immunoprecipitation experiments and cell binding studies, alloantisera were shown to contain antibodies to both the RT1.B and the RT1.D gene products.
Ronald D. Guttmann +2 more
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Differential expression of major histocompatibility complex class II antigens on human keratinocytes [PDF]
Journal of the American Academy of Dermatology, 1988 Skin biopsies from 136 patients with 30 different dermatoses and eight biopsies of normal skin were investigated with the avidin-biotin-peroxidase complex method with regard to the expression of major histocompatibility complex class II antigens human leukocyte antigen (HLA) HLA-DR, HLA-DQ, HLA-DP on keratinocytes.
Heinz Niedecken +3 more
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Expression of major histocompatibility complex class II antigens in the canine intestine
Veterinary Immunology and Immunopathology, 1998Immunohistochemical techniques were used to assess major histocompatibility complex (MHC) class II expression by enterocytes and lamina propria cells in the canine intestinal tract. Duodenal enterocyte class II expression was faint and limited to the lower crypt region whereas jejunal and ileal enterocyte expression was stronger, being present in both ...
Edward J Hall +3 more
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Structure and Polymorphism of Murine and Human Class II Major Histocompatibility Antigens
Immunological Reviews, 1985The molecular analysis of the Class II region of the MHC of mice and of humans has to date led to some important conclusions. These regions encode sizeable families of related loci, at least 2 alpha and 6 beta in mice and 6 alpha and 7 beta in man. In addition to the sizeable number of potential molecules that could be expressed by the loci of this ...
Hugh O. McDevitt +2 more
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Class II major histocompatibility antigens and the etiology of systemic lupus erythematosus
Clinical Immunology and Immunopathology, 1983It is hypothesized that the underlying immunoregulatory dysfunction in systemic lupus erythematosus (SLE) is altered recognition by T cells of self class II major histocompatibility antigens (Ia). The resultant cellular autoreactivity would directly cause certain of the immunopathological manifestations of SLE. The perception by T cells of self non-MHC
Philip L. Cohen, Robert A. Eisenberg
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Peptide binding and antigen presentation by class II histocompatibility glycoproteins
Biopolymers, 1997The immune system has evolved complex mechanisms for the recognition and elimination of pathogens. CD4+ helper T lymphocytes play a central role in orchestrating immune responses and their activation is carefully regulated. These cells selectively recognize short peptide antigens stably associated with membrane-bound class II histocompatibility ...
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Cross-reactions of Class II Histocompatibility Antigens of Various Species [PDF]
, 1986 A major histocompatibility complex (MHC) has been demonstrated in all mammalian and avian species studied and in several fish and amphibian species. Interestingly, the MHC loci occur in a homologous linkage group in various species. Whether such conservation of a linkage group during the evolution of species is due to chance or is of functional ...
P. Ivanyi, M. Pla
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Journal of Clinical Immunology, 1988
Class II antigens encoded by genes of the major histocompatibility complex (MHC) are expressed by a variety of cell types and have a vital role in the cellular interactions required for an effective immune response. We have analyzed the regulation of HLA-DR, DP, and DQ class II antigen expression on cells of different lineage from an immunodeficient ...
E. Richard Stiehm +7 more
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Class II antigens encoded by genes of the major histocompatibility complex (MHC) are expressed by a variety of cell types and have a vital role in the cellular interactions required for an effective immune response. We have analyzed the regulation of HLA-DR, DP, and DQ class II antigen expression on cells of different lineage from an immunodeficient ...
E. Richard Stiehm +7 more
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ALLOSPECIFIC MONOCLONAL ANTIBODIES RECOGNIZING RAT CLASS I AND CLASS II HISTOCOMPATIBILITY ANTIGENS
Transplantation, 1982Rat-mouse hybridomas have been developed producing monoclonal antibodies which recognize rat major histocompatibility complex specificities. Splenic lymphocytes from a LEW (RT1l) rat alloimmunized against ACI (Rt1a) splenocytes were used for hybridoma production.
Edward E. Engel +2 more
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