Results 371 to 380 of about 453,877 (390)

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

Nature, 1988
Class II and class I histocompatibility molecules allow T cells to recognize 'processed' polypeptide antigens. The two polypeptide chains of class II molecules, alpha and beta, are each composed of two domains (for review see ref. 6); the N-terminal domains of each, alpha 1 and beta 1, are highly polymorphic and appear responsible for binding peptides ...
Don C. Wiley, Pamela J. Bjorkman, Pamela J. Bjorkman, Mark A. Saper, Boudjéma Samraoui, Jerry H. Brown, Theodore S. Jardetzky   +6 more
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Class II Antigens of the Human Major Histocompatibility Complex

1987
Progress in the biological sciences has been remarkable during the past several decades. As the level of sophisticated knowledge expands it becomes difficult if not impossible for the individual investigator to master but a tiny segment of current biology.
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Chapter 24 Monitoring Macroautophagy by Major Histocompatibility Complex Class II Presentation of Targeted Antigens

2009
Major histocompatibility complex (MHC) class I and II molecules can both present cytosolic and nuclear antigens to CD8(+) and CD4(+) T cells, respectively. However, MHC class I displays proteasomal, whereas MHC class II molecules display lysosomal, degradation products. One pathway by which intracellular antigens gain access to lysosomal degradation is
Gannagé, M, Münz, C
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Modulation of Class I and Class II Major Histocompatibility Complex Antigens in Gliomas

1987
The concept of major histocompatibility complex (MHC) proposed by Gorer in 1937 (1) has been intensively developped in the last twenty years. Denoted H-2 in mice and HLA (Human Lymphocyte Locus A) in humans, it is a well defined locus on chromosome 17 in mice and on the short arm of chromosome 6 in humans.
N. de Tribolet, Patrick L.F. Zuber
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Upregulation of major histocompatibility complex class II antigens in hepatocytes in Doberman hepatitis

Veterinary Immunology and Immunopathology, 2003
Major histocompatibility complex (MHC) class II antigen expression in hepatocytes and its correlation with mononuclear cell infiltration into the liver were studied using immunohistochemical techniques in 38 Dobermans with Doberman hepatitis (DH). Liver biopsy samples were obtained from 18 dogs at the subclinical stage.
M. Speeti, A. Ståhls, Seppo Meri, Elias Westermarck   +3 more
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Molecular analysis of the genes for human class II antigens of the major histocompatibility complex

Human Immunology, 1983
Different cDNA clones have been isolated that encode each of the three chains of HLA-DR antigens: alpha, intermediate and beta, as well as another beta chain, most likely DC. Whereas the DR alpha and intermediate chains seem encoded by single genes, the DR and DC beta chains are most likely encoded by multiple genes; furthermore, their polymorphism can
Chantal Rabourdin-Combe, Eric O. Long, Jack Gorski, Claire T. Wake, Michel Strubin, Pierre Rollini, Bernard Mach   +6 more
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Delivery of exogenous antigen into the major histocompatibility complex class I and class II pathways by electroporation

Journal of Leukocyte Biology, 1994
Abstract Exogenous, nonreplicating protein antigens (Ags) are usually taken up by antigen-presenting cells (APCs) via endocytosis or pinocytosis and enter the major histocompatibility complex (MHC) class II processing and presentation pathway.
Yong Ke, Judith A. Kapp, Paul D. Gottlieb, Ying Li, Ying Li   +4 more
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Expression of major histocompatibility complex class I and class II antigens in canine masticatory muscle myositis

Neuromuscular Disorders, 2007
Studies in human immune-mediated inflammatory myopathies have documented expression of major histocompatibility complex class I (MHC class I) and class II (MHC class II) antigens on muscle fiber membranes in the presence or absence of cellular infiltration.
PACIELLO, ORLANDO, G.D. Shelton, PAPPARELLA, SERENELLA   +2 more
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B-L antigens (Class II) of the chicken major histocompatibility complex control T-B cell interaction

Immunogenetics, 2004
O. Vainio, C. Koch, A. Toivanen
semanticscholar   +1 more source

Keratinocyte class II histocompatibility antigen expression

British Journal of Dermatology, 1985
Teresa Y. Basham, Brian J. Nickoloff, Vera B. Morhenn, Thomas C. Merigan   +3 more
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