Results 71 to 80 of about 1,108,608 (357)

Study of Sperm Parameters and Sperm Fertility in Mice were Exposed to Tamoxifen during Embryonic Development

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2017
Introduction: Tamoxifen is steroidal drug, which mainly treats breast cancer and also used to stimulate ovulation. The purpose of the present study was the evaluation of sperm parameters and fertility of mice whose mothers had received tamoxifen during ...
J Soleimanirad, l Roshangar, M Abouzaripour, E Daneshi   +3 more
doaj  

Annual variation in the levels of transcripts of sex-specific genes in the mantle of the common mussel, Mytilus edulis [PDF]

, 2012
Mytilus species are used as sentinels for the assessment of environmental health but sex or stage in the reproduction cycle is rarely considered even though both parameters are likely to influence responses to pollution.
A Gorbman, A Hines, A Hines, A Scarpato, A Tanguy, A Viarengo, A Wacker, AM Debruyn, B Gaylord, BE Galindo, CM Ciocan, CM Ciocan, CM Ciocan, D de Longcamp, D Fernandes, D Le Guellec, DE Morse, DJ Waxman, DR Livingstone, ED Goldberg, F Gazeau, GG Lauenstein, GN Eick, HG Choi, I Zorita, J Burger, Jack Anthony Gilbert, JF Narbonne, John A. Craft, K Inoue, K Ramu, KC Srivastava, KJ Livak, M Banni, M Banni, M Brown, M Ortiz-Zarragoitia, M Osada, M Shoji, M Torrado, MF Martinez, MH Devier, PP Fong, PP Fong, PS York, R Barra, R Lazzara, RT Counihan, S Carreau, S Fasulo, Sandhya Anantharaman, SF Cummins, SP Boyle, T Matsutani, T Onitsuka, T Takagi, T Tanabe, VD Vacquier, W Sedik   +58 more
core   +3 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Lipid droplet accumulation in microglia and their potential roles

Lipids in Health and Disease
Microglia are the resident immune cells of the central nervous system (CNS), where lipid metabolism is critical for maintaining homeostasis. In response to various external stimuli, they demonstrate a range of phenotypic expressions and lipid metabolic ...
Yunxia Li, Qi Zhao, Yan Wang, Wenyi Du, Riyun Yang, Jian Wu, Yi Li   +6 more
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Machine learning approach for segmenting glands in colon histology images using local intensity and texture features

, 2019
Colon Cancer is one of the most common types of cancer. The treatment is planned to depend on the grade or stage of cancer. One of the preconditions for grading of colon cancer is to segment the glandular structures of tissues. Manual segmentation method
Chatterjee, Soumick, Khatun, Rupali
core   +1 more source

Anatomy and Histology of the Male Reproductive Complex of the Onion Maggot Fly, \u3ci\u3eDelia Antiqua\u3c/i\u3e, (Diptera: Anthomyiidae) Including Some Comparisons With \u3ci\u3eD. Platura\u3c/i\u3e and \u3ci\u3eD. Radicum\u3c/i\u3e [PDF]

, 2018
In Delia antiqua (Meigen) (Diptera: Anthomyiidae), the male reproductive complex is composed of a pair of testes, paired vas deferens connecting the testes to the anterior ejaculatory duct, and a pair of paragonial (accessory) glands. Each D.
Grimnes, Karin A, Miller, James R
core   +2 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Study on the Morphology of Fasciola gigantica and Economic Losses due to Fasciolosis in Berau, East Kalimantan

Biosaintifika: Journal of Biology & Biology Education, 2019
Fasciolosis is one of the endemic parasitic diseases in Indonesia and causes significant economic losses. Fasciola gigantica is the main species found to infect livestock. This research aimed to describe the morphology of F.
Muhammad Rofi' Prasetya, Setiawan Koesdarto, Nunuk Dyah Retno Lastuti, Lucia Tri Suwanti, Kusnoto Kusnoto, Muchammad Yunus   +5 more
doaj   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source