Results 91 to 100 of about 33,260 (245)
Protein encoded by oncogene 6b from Agrobacterium tumefaciens has a reprogramming potential and histone chaperone-like activity [PDF]
, 2014 Crown gall tumors are formed mainly by actions of a group of genes in the T-DNA that is transferred from Agrobacterium tumefaciens and integrated into the nuclear DNA of host plants.
Chiyoko Machida +4 more
core +2 more sources
Histone chaperone regulates replication
The Journal of Cell Biology, 2008 Histone supply and demand are tightly coupled at the replication fork by a chaperone, according to Genevieve Almouzni (Curie Institute, Paris, France) and colleagues. The chaperone, Asf1, passes histones from parental to daughter DNA strands and unwinds just enough DNA to match its transfer activities.
openaire +2 more sources
Advanced Science, EarlyView.NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang +12 more
wiley +1 more source
HERVs, transposons and human diseases : part II [PDF]
, 2013 Part 1 and part 3 of the article can be found through this link : https://www.um.edu.mt/library/oar//handle/123456789/12961 https://www.um.edu.mt/library/oar//handle/123456789/13132Part 2 of the article.
Baldacchino, Sandra, Grech, Alfred
core +2 more sources
UBR7 acts as a histone chaperone for post‐nucleosomal histone H3
The EMBO Journal, 2021 Histone chaperones modulate the stability of histones beginning from histone synthesis, through incorporation into DNA, and during recycling during transcription and replication. Following histone removal from DNA, chaperones regulate histone storage and degradation.
Ann K Hogan +16 more
openaire +2 more sources
Advanced Intelligent Discovery, EarlyView.scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta +3 more
wiley +1 more source
HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX. [PDF]
PLoS ONE, 2018 The centromere specific histone H3 variant CENP-A/CENH3 specifies where the kinetochore is formed in most eukaryotes. Despite tight regulation of CENP-A levels in normal cells, overexpression of CENP-A is a feature shared by various types of solid tumors
Jonathan Nye +3 more
doaj +1 more source
Histone chaperones: Variety and functions
Moscow University Biological Sciences Bulletin, 2016 Histone chaperones are required for the formation of the nucleosome—the basic unit of chromatin that consists of the DNA and histones. In this review, participation of histone chaperones CAF-1, ASF1, NAP1, and FACT in key cellular processes is discussed.
M. E. Valieva +2 more
openaire +2 more sources
A potential histone-chaperone activity for the MIER1 histone deacetylase complex
Nucleic Acids Research, 2023 Abstract Histone deacetylases 1 and 2 (HDAC1/2) serve as the catalytic subunit of six distinct families of nuclear complexes. These complexes repress gene transcription through removing acetyl groups from lysine residues in histone tails.
Wang, S. +7 more
openaire +3 more sources
Animal Models and Experimental Medicine, EarlyView.This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin +2 more
wiley +1 more source