immunoHuMiX: A personalizable gut‐on‐chip model for unraveling human microbiome–immune interactions
The study introduces a personalized gut model that brings together human immune cells and intestinal cells to better mimic how the body interacts with microbes. This system successfully maintained both human cells and a 17‐strain probiotic community, showing consistent immune responses across different donors.
Charlotte De Rudder +26 more
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Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases. [PDF]
Zhang LY +4 more
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Identification of Histone Deacetylase Inhibitor Targeting Type I Interferon and B Cell Abnormalities in Systemic Lupus Erythematosus. [PDF]
Hirayama T +16 more
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Recent Insights into the Creation of Histone Deacetylase Inhibitors for the Treatment of Human Diseases. [PDF]
Yudaev P, Aleksandrova Y, Neganova M.
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Targeted Degradation of Histone Deacetylase 8 Using Proteolysis Targeting Chimeras Technology: A Promising Approach for Glioblastoma Treatment. [PDF]
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LDN-57444 sensitizes hepatocellular carcinoma cells to sorafenib by promoting ferroptosis through histone deacetylase 2 (HDAC2) inhibition. [PDF]
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Histone deacetylase 4: A therapeutic target for cardiovascular diseases (Review). [PDF]
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European Journal of Medicinal Chemistry, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
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