Results 141 to 150 of about 138,704 (292)

Design, synthesis, and biological evaluation of phenylisoxazole-based histone deacetylase inhibitors. [PDF]

PLoS One
Qin X, Han M, Hu P, Que H, Shao Z, Yan D.   +5 more
europepmc   +1 more source

Hypophosphatemia as a Potential Class Effect of Histone Deacetylase Inhibitors: Evidence from Disproportionality Analysis and Mendelian Randomization Analysis of Drug Targets. [PDF]

Pharmaceuticals (Basel)
Zhao R, Zhang B, Han M, Lv M, Sun J, Zhou X.   +5 more
europepmc   +1 more source

Recent Insights into the Creation of Histone Deacetylase Inhibitors for the Treatment of Human Diseases. [PDF]

Int J Mol Sci
Yudaev P, Aleksandrova Y, Neganova M.
europepmc   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

International Journal of Cancer, EarlyView.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari, Pablo Hoffmann, Laura Reichl, Maximilian Schmutz, Nina Fischer, Thi Tuong Vi Dang, Fulvia Ferrazzi, Pascal Johann, Michaela Kuhlen, Constantin Lapa, Rainer Claus   +10 more
wiley   +1 more source

Histone deacetylase inhibitors sensitize glioblastoma models to temozolomide and reprogram immunosuppressive myeloid cells. [PDF]

Sci Rep
Tehrani GA, Kubick RN, Zarodniuk M, Datta M.   +3 more
europepmc   +1 more source

The potential use of histone deacetylase inhibitors in the treatment of depression.

Progress in Neuro-psychopharmacology and Biological Psychiatry, 2016
Manabu Fuchikami, Shigeto Yamamoto, S. Morinobu, S. Okada, Yosuke Yamawaki, S. Yamawaki   +5 more
semanticscholar   +1 more source

Advances in Immunological Combination Therapy for Colorectal Cancer

iMetaMed, EarlyView.
Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu, Rongbo Wen, Tianshuai Zhang, Fuao Cao, Xiaoming Zhu, Liqiang Hao, Wei Zhang, Guanyu Yu   +7 more
wiley   +1 more source

Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review). [PDF]

Int J Mol Med
Wang J, Zhao Q, Zhang S, Liu J, Fan X, Han B, Hou Y, Ai X.   +7 more
europepmc   +1 more source

Harnessing microbial metabolism and nutrition to target the gut–mammary axis for better livestock production and health

iMetaOmics, EarlyView.
The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou, Cheng Guo, Mahmoud M. Abdelsattar, Ahmad R. Musa, Mequanint Biks, Abdullahi A. Musa, Shahnaz Rahman, Abera Teshome Aleli, Pei Zhong, Jiawei Zhang, Junwei Cui, Xiyan Kou, Qingyuan Yu, Caijuan Yue, Qin Li, Dan Zhang, Zixuan Peng, Ao Ren, Ziqi Tian, Ziqi Liu, Yaona Zhang, Lili Zhang, Dina Karmallah, Naifeng Zhang, Tao Ma, Yan Tu, Qiyu Diao, Guijie Zhang, Xiaofeng Xu, Yanliang Bi   +29 more
wiley   +1 more source

Potential risks of histone deacetylase inhibitors in cancer therapeutics and feasible combination therapeutic strategies. [PDF]

World J Clin Oncol
Xiao S, Xu XZ, Liao M, Song DD, Tang JF, Zhou CF.   +5 more
europepmc   +1 more source