Results 151 to 160 of about 776,666 (283)

Screening and evaluation of potential histone deacetylase inhibitors against Babesia infections. [PDF]

Int J Parasitol Drugs Drug Resist
Zhang X, Li Y, Che J, Wang J, Liang Q, Zhang Y, Bai Y, Zhao S, Yin H, Wang J, Guan G.   +10 more
europepmc   +1 more source

Starch nanoparticles for delivery of the histone deacetylase inhibitor CG-1521 in breast cancer treatment

, 2019
Esma Alp,1–4 Fehmi Damkaci,2 Eylem Guven,1 Martin Tenniswood3,4 1Department of Nanotechnology and Nanomedicine, Hacettepe University, Beytepe, Ankara 06800, Turkey; 2Department of Chemistry, State University of New York at Oswego, Oswego, NY 13126,
Damkaci F, Tenniswood M, Guven E, Alp E
core  

Correction: Histone deacetylase inhibitors are protective in acute but not in chronic models of ototoxicity. [PDF]

Front Cell Neurosci
Yang CH, Liu Z, Dong D, Schacht J, Arya D, Sha SH.   +5 more
europepmc   +1 more source

Design, synthesis, and antitumor evaluation of histone deacetylase inhibitors with L-phenylglycine scaffold

, 2015
Yingjie Zhang,1 Xiaoguang Li,1 Jinning Hou,1 Yongxue Huang,2 Wenfang Xu1 1Department of Medicinal Chemistry, School of Pharmacy, Shandong University, Ji’nan, 2Weifang Bochuang International Biological Medicinal Institute, Weifang, Shandong, People&
Li X, Hou J, Huang Y, Zhang Y, Xu W
core  

Design, Synthesis, In Vitro Evaluation, and Molecular Docking of 4-Substituted Anilides as Histone Deacetylase Inhibitors and Potential Anticancer Agents. [PDF]

Chem Biodivers
Lisouskaya M, Panibrat A, Kayumov M, Yuldashev K, Syakhovich V, Mikhal'chuk A.   +5 more
europepmc   +1 more source

Serotonin neuromicrobiology: Psychobiotic modulation of the gut–brain axis for mental health

Ibrain, EarlyView.
An overview of Psychobiotics and Tryptophan metabolism: A serotonin‐kynurenine crosstalk shaping the Gut‐Brain axis. IDO1, Indoleamine 2,3‐dioxygenase 1; 5‐HT3, 5‐hydroxytryptamine type 3; IFN‐γ, Interferon‐gamma; TNF‐α, Tumor necrosis factor‐alpha; IL‐1β, Interleukin‐1 beta; IL‐6, Interleukin 6; Trp, Tryptophan; 5‐HT, 5‐hydroxy‐tryptamine; 5‐HTP, 5 ...
Nidhi Mandloi, Aarzoo, Chakkaravarthi Saravanan, Heera Ram, Bhim Pratap Singh   +4 more
wiley   +1 more source

Recommended Tool Compounds: Isoform- and Class-Specific Histone Deacetylase Inhibitors. [PDF]

ACS Pharmacol Transl Sci
Schäker-Hübner L, Hansen FK.
europepmc   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

International Journal of Cancer, EarlyView.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari, Pablo Hoffmann, Laura Reichl, Maximilian Schmutz, Nina Fischer, Thi Tuong Vi Dang, Fulvia Ferrazzi, Pascal Johann, Michaela Kuhlen, Constantin Lapa, Rainer Claus   +10 more
wiley   +1 more source

[Expression of Concern] Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects. [PDF]

Int J Oncol
Carlisi D, Vassallo B, Lauricella M, Emanuele S, D'anneo A, Di Leonardo E, Di Fazio P, Vento R, Tesoriere G.   +8 more
europepmc   +1 more source

Cross‐Regulation Between DNA Methylation and Circadian Clock Reprogramming in Ovarian Cancer: Mechanistic Insights, Biomarker Potential, and Therapeutic Implications

International Journal of Cancer, EarlyView.
ABSTRACT Early diagnosis remains challenging, recurrence rates remain high, and platinum resistance frequently develops in ovarian cancer (OC), collectively representing major barriers to long‐term patient survival. DNA methylation (DNAm), as a relatively stable yet dynamically modifiable epigenetic signature, can capture alterations in tumor states ...
Min Xing, Chang Zhou, Yi Tang, Shuhui Xu, Shasha Zhou, Weiai Liu, Huiping Liu   +6 more
wiley   +1 more source