Results 171 to 180 of about 138,704 (292)

Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways

Autophagy, 2015
Jianbin Zhang, Shukie Ng, Jigang Wang, Jing Zhou, S. Tan, Naidi Yang, Q. Lin, Dajing Xia, Han-Ming Shen   +8 more
semanticscholar   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari, Hadi Sedigh Ebrahim‐Saraie, Majid Taati Moghadam, Meysam Hasannejad‐Bibalan   +3 more
wiley   +1 more source

Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells. [PDF]

Cancer Res Commun
Koppenhafer SL, Geary EL, Thomas MV, Croushore EE, Zimmerman JAO, Gedminas JM, Quelle DE, Dodd RD, Gordon DJ.   +8 more
europepmc   +1 more source

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz e Magalhães, Elizabeth Luciana Marinho Miguel, Larissa Vieira Toledo, Débora Ribeiro Orlando, Alan Rodrigues Teixeira Machado, Bruno Del Bianco Borges, Luciano José Pereira, Marco Fabrício Dias‐Peixoto, Eric Francelino Andrade   +9 more
wiley   +1 more source

Histone Deacetylase Inhibitors for Peripheral T-Cell Lymphomas. [PDF]

Cancers (Basel)
Irimia R, Piccaluga PP.
europepmc   +1 more source

Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells.

Journal of the National Cancer Institute, 2000
PA Marks, V. Richon, R. Rifkind
semanticscholar   +1 more source

Citrus depressa peel extract and its polymethoxyflavones mitigate acetaminophen‐induced chronic liver injury in mice through antioxidant activation, epigenetic regulation, and gut microbiota modulation

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Preventing chronic liver damage is essential for maintaining overall health and reducing the risk of serious liver diseases. Acetaminophen (APAP) overdose can lead to severe liver damage due to oxidative stress, and citrus fruits are rich in bioactive compounds that may have health benefits.
Po‐Yao Tsai, Zi‐Han Lin, Guor‐Jien Wei, Liang‐Yi Wu, Tien‐Yuan Wu, Yen‐Chen Tung, Ssu‐Han Huang, Zheng‐Yuan Su   +7 more
wiley   +1 more source

Metformin sensitizes triple-negative breast cancer to histone deacetylase inhibitors by targeting FGFR4. [PDF]

J Biomed Sci
Gu Z, Ye F, Luo H, Li X, Gong Y, Mao S, Jia X, Han X, Han B, Fu Y, Cheng X, Li J, Shao Z, Wen P, Hu X, Zhuang Z.   +15 more
europepmc   +1 more source

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source