Results 161 to 170 of about 138,704 (292)

Histone deacetylase inhibitors in multiple myeloma: from bench to bedside

International journal of hematology, 2016
T. Harada, T. Hideshima, K. Anderson
semanticscholar   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

Histone Deacetylase Inhibitors Promote the Anticancer Activity of Cisplatin: Mechanisms and Potential. [PDF]

Pharmaceuticals (Basel)
Zhou Y, Luo Q, Gu L, Tian X, Zhao Y, Zhang Y, Wang F.   +6 more
europepmc   +1 more source

Histone Deacetylase Inhibitors: Overview and Perspectives

Molecular Cancer Research, 2007
Milos Dokmanovic, Cathy Clarke, P. Marks
semanticscholar   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Mechanisms of resistance to histone deacetylase inhibitors in acute leukemia. [PDF]

Ther Adv Hematol
Akbarzadeh MA, Vaez-Gharamaleki Y, Hosseini MS.   +2 more
europepmc   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

Synthesis, In Silico, and Biological Evaluation of Non-Hydroxamate Benzoic Acid-Based Derivatives as Potential Histone Deacetylase Inhibitors (HDACi). [PDF]

Chem Biodivers
Al Rahim NAA, Mahmood AAR, Tahtamouni LH, Bawadi RM, Almasri AY, Hamad MA, Hussein NA, Yasin SR, Saleh AM.   +8 more
europepmc   +1 more source

Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells

Interdisciplinary Medicine, EarlyView.
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen, Jiayi Wang, Jimin Yu, Yiran Zhou, Lihai Liu, Jing Liu, Liang Wang   +6 more
wiley   +1 more source

Characteristic analysis of adverse reactions of histone deacetylase inhibitors based on WHO-VigiAccess. [PDF]

Front Pharmacol
Yin T, Liu Y, Li C, Feng X, Lin Y, Qu Z.
europepmc   +1 more source