Results 211 to 220 of about 98,638 (334)

Gene Expression Profiling of Multiple Histone Deacetylases (HDAC) and Its Correlation with NRF2-Mediated Redox Regulation in the Pathogenesis of Diabetic Foot Ulcers [PDF]

, 2020
Teena Rajan, Dhamodharan Umapathy, Daoud Ali, Rajesh Kesavan, Kunka Mohanram Ramkumar   +4 more
openalex   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review). [PDF]

Oncol Rep
Suwanwong Y, Ploensil P.
europepmc   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Histone Deacetylases in Neurodegenerative Diseases and Their Potential Role as Therapeutic Targets: Shedding Light on Astrocytes. [PDF]

Pharmaceuticals (Basel)
Pinheiro PSM, Diniz LP, Franco LS, Siqueira M, Gomes FCA.   +4 more
europepmc   +1 more source

Dual targeting of Phosphoinositide 3-Kinase (PI3K) and histone deacetylase 6 (HDAC6) in cancer

Sami Hamdoun, Nafees Ahemad, Sharifah Aminah Syed Mohamad   +2 more
openalex   +1 more source

A Focus on the Preclinical Development and Clinical Status of the Histone Deacetylase Inhibitor, Romidepsin (Depsipeptide, Istodax^®)

, 2012
Simon J. Harrison, Mark Bishton, Susan E. Bates, Steven Grant, Richard Piekarz, Ricky W. Johnstone, Yun Dai, Becki Lee, Maria Elisa Melo Branco de Araújo, H. Miles Prince   +9 more
openalex   +2 more sources

Histon-Deacetylase [PDF]

, 2018
openaire   +1 more source

Role of Antimicrobial Peptides in the Pathogenesis of Atopic Dermatitis

The Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by barrier dysfunction, immune dysregulation, and microbial dysbiosis. Recent studies have highlighted the multifaceted roles of antimicrobial peptides (AMPs) both as innate defenders against microbial invasion and as regulators of immune responses and skin barrier ...
Ge Peng, Alafate Abudouwanli, Quan Sun, Yi Tan, Wanchen Zhao, Mengyao Yang, Shan Wang, Hideoki Ogawa, Ko Okumura, François Niyonsaba   +9 more
wiley   +1 more source

Inhibition of Histone Deacetylases Induces Cancer Cell Apoptosis Through the PERK Pathway of ER Stress Response. [PDF]

J Cell Mol Med
Wang X, Yang C, Yang Y, Xu F, Yuan D, Gu Y.   +5 more
europepmc   +1 more source