Results 261 to 270 of about 360,616 (327)

Catechins and Their Effect on the Gut Microbiome in Health and Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Catechins are a group of flavonoids found primarily in green tea, fruits, and berries; they play a significant role in the modulation of the gut microbiota, thereby having an impact on gut health and cancer prevention. Owing to their low bioavailability, catechins are transformed by the gut microbiota into various bioactive metabolites such as
Prakash Monika, Bindu Sadanandan, Honnamachanahalli Ramachandraiah Tejashree, Maitreyi Darbha, Kirti Gupta, Srinivas Reneeka   +5 more
wiley   +1 more source

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source

Epigenomics Nutritional Insights of <i>Crocus sativus</i> L.: Computational Analysis of Bioactive Molecules Targeting DNA Methyltransferases and Histone Deacetylases. [PDF]

Int J Mol Sci
Piergentili A, Saraceni PR, Demurtas OC, Benassi B, Arcangeli C.   +4 more
europepmc   +1 more source

Schisandrin C Targets PPARγ to Induce Ferroptosis in Colorectal Cancer Cells and Promote M1 Macrophage Polarization

Phytotherapy Research, EarlyView.
Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei, Hong‐Ping Wen, Jian‐Bo Song, Jin‐Fang Xu, Hong‐Rui Guo   +4 more
wiley   +1 more source

HIV-1 accessory protein Vpr possesses a cryptic p300-dependent transcription-promoting activity that is blocked by histone deacetylases in CD4+ T cells. [PDF]

PLoS Pathog
Lewis CA, Margolis DM, Browne EP.
europepmc   +1 more source

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Metformin Increased Histone Deacetylases 1, 3, and 8 Expressions as Epigenetic Regulators in Type 2 Diabetic Patients. [PDF]

Rep Biochem Mol Biol
Izadi A, Zarourati A, Boozarpour S, Ghalandar M, Lashkarboloki M, Momeni Moghaddam M, Lashkarboloki M.   +6 more
europepmc   +1 more source

Histone deacetylases in the regulation of cell death and survival mechanisms in resistant BRAF-mutant cancers. [PDF]

Cancer Drug Resist
Biersack B, Nitzsche B, Höpfner M.
europepmc   +1 more source

Role of histone deacetylases and sirtuins in the ischaemic stroke: a protocol for a systematic review and meta-analysis of animal studies. [PDF]

Stroke Vasc Neurol
Majdi A, Mostafavi H, Moharrami A, Yaraghi S, Ghaffari Tabrizi A, Dojahani M, Alirezapour E, Mansori K.   +7 more
europepmc   +1 more source

Histone deacetylases: potential therapeutic targets in cisplatin-induced acute kidney injury. [PDF]

Ann Med
Guo S, Zhao J, Zhang Y, Qin Y, Yuan J, Yu Z, Xing Y, Zhang Y, Hui Y, Wang A, Han M, Zhao Y, Ning X, Sun S.   +13 more
europepmc   +1 more source