Results 271 to 280 of about 98,157 (333)

Histone Deacetylase 3 [PDF]

, 2020
openaire   +1 more source

Targeting Inflammation and Immune Regulation in Chronic Inflammation Associated Cancers

Cancer Science, EarlyView.
Chronic inflammation sustains activation of key inflammatory pathways, including Nuclear factor kappa B (NF‐κB), Interleukin‐6‐signal transducer and activator of transcription 3 (IL6‐STAT3), Phosphoinositide 3‐kinase/Akt (PI3K/Akt), and Wingless/β‐catenin (Wnt/β‐catenin) signaling. This promotes immune dysregulation through the expansion and functional
Lawan Rabiu, Mengzhu Chinn, Feng Chen, Yerkezhan Yerkinkazhina, Yuan Tian, Wei‐Guo Zhu   +5 more
wiley   +1 more source

Hitting Two Birds With One Stone: Dual Modulation of Brain Carbonic Anhydrases and Histone Deacetylases Boosts Memory Consolidation. [PDF]

Arch Pharm (Weinheim)
Costa A, Bozdag M, Renzi G, Rani B, Passani MB, Angeli A, Provensi G, Carta F, Supuran CT.   +8 more
europepmc   +1 more source

A Focus on the Preclinical Development and Clinical Status of the Histone Deacetylase Inhibitor, Romidepsin (Depsipeptide, Istodax^®)

, 2012
Simon J. Harrison, Mark Bishton, Susan E. Bates, Steven Grant, Richard Piekarz, Ricky W. Johnstone, Yun Dai, Becki Lee, Maria Elisa Melo Branco de Araújo, H. Miles Prince   +9 more
openalex   +2 more sources

Histone Deacetylase 4 [PDF]

, 2020
openaire   +1 more source

Application Strategies of Bone Marrow Mesenchymal Stromal Cells in Bone‐Related Diseases

Cell Proliferation, EarlyView.
Engineered BMSCs and vesicles enhance therapy effects for bone diseases via multi‐strategic approaches. ABSTRACT Bone‐related diseases (e.g., osteoporosis, osteoarthritis and fractures) exhibit a rising global incidence, imposing significant burdens on both quality of life and healthcare systems.
Xuemei Long, Dan Tan, Qianke Tao, Qiaonan Ye, Luwen Ye, Qing Li, Jingang Xiao   +6 more
wiley   +1 more source

Inhibition of histone deacetylases 3 attenuates imiquimod-induced psoriatic dermatitis via targeting cGAS-STING signaling in keratinocytes. [PDF]

J Transl Med
Zeng C, Wen X, Wei Z, Dong X.
europepmc   +1 more source

Histone deacetylase (HDAC) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Intrinsic specificity of a ‘core’ TIP60 acetyltransferase complex in Drosophila

The FEBS Journal, EarlyView.
The intrinsic substrate selectivity of the Drosophila TIP60‐core acetyltransferase was determined using synthetic nucleosome arrays. Targeted mass spectrometry revealed site‐specific acetylation of histones H2A, H2A.V, and H4, uncovering distinct acetylation rates and patterns across individual lysines.
Silke Krause, Marco Borsò, Marisa Müller, Axel Imhof, Zivkos Apostolou, Peter B. Becker   +5 more
wiley   +1 more source

Histone deacetylases: potential therapeutic targets in cisplatin-induced acute kidney injury. [PDF]

Ann Med
Guo S, Zhao J, Zhang Y, Qin Y, Yuan J, Yu Z, Xing Y, Zhang Y, Hui Y, Wang A, Han M, Zhao Y, Ning X, Sun S.   +13 more
europepmc   +1 more source