Results 281 to 290 of about 98,638 (334)

Biophysical Mechanism of the SAHA Inhibition of Zn<sup>2+</sup>-Histone Deacetylase-Like Protein (FB188 HDAH) Assessed via Crystal Structure Analysis

, 2018
Cynthia R. Trejo‐Muñoz, Ricardo Vázquez‐Ramírez, Luis Mendoza, Carlos Kubli‐Garfias   +3 more
openalex   +2 more sources

Histone deacetylase (HDAC) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Role of histone deacetylases in neuroplasticity impairments and inflammation in major depression. [PDF]

Neurosci Appl
Garayo-Larrea A, Azqueta A, Tordera RM.
europepmc   +1 more source

Valproic acid for treatment of traumatic brain injury: Study protocol for the VIBRANT prospective randomized trial

Transfusion, EarlyView.
Abstract Background Traumatic brain injury (TBI) carries significant mortality and morbidity in civilian and military populations. Current treatment guidelines for TBI are primarily supportive, and no pharmacological agent exists to attenuate the progression of brain injury.
Maxime A. Visa, Marjorie R. Liggett, Sharnia Lashley, Umar Bhatti, Zaiba A. Dawood, Alvin Anand, Nathan P. Gill, Denise M. Scholtens, Bowen Wang, Hasan B. Alam   +9 more
wiley   +1 more source

Advanced Progress of Histone Deacetylases in Rheumatic Diseases. [PDF]

J Inflamm Res
Liu XM, Yang L, Yang QB.
europepmc   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

Cumulative evidence for associations between variants in the histone deacetylases genes and cardio-cerebrovascular diseases: A systematic review and meta-analysis. [PDF]

JRSM Cardiovasc Dis
Gu D, Li R, Deng K, Chen W, Han B, Zeng Z.   +5 more
europepmc   +1 more source

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation

Experimental Physiology, EarlyView.
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh, Amir Arsalan Ghahari, Ehsan Zandi, Seyedeh Zeynab Rasouli, Shaghayegh Davari, Mobina Hoseinzadeh, Mir Alireza Nourazar   +6 more
wiley   +1 more source

Chemical Versatility in Catalysis and Inhibition of the Class IIb Histone Deacetylases. [PDF]

Acc Chem Res
Christianson DW.
europepmc   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source