Results 291 to 300 of about 98,157 (333)

LIN28A blocks the EndMT process of high glucose‐induced HRMECs by stabilizing SIRT6 mRNA

open access: yesJournal of Diabetes Investigation, EarlyView.
LIN28A promotes mRNA stability of SIRT6 to activate the AMPK signaling, thereby inhibiting the EndMT process induced by HG in HRMECs. ABSTRACT Background Diabetic retinopathy (DR) is a microvascular condition resulting from microangiopathy, causing gradual retinal damage and potential blindness.
Xueying Wang   +5 more
wiley   +1 more source

A leucine‐rich‐repeat receptor‐like kinase SERL1 phosphorylates and stabilizes OsALDH2B1 to promote alkaline tolerance and grain size in rice

open access: yesJournal of Integrative Plant Biology, EarlyView.
The rice aldehyde dehydrogenase OsALDH2B1 enhances grain size and tolerance to alkaline soil by repressing GRAIN SIZE 3 and activating catalases. SERL1‐mediated phosphorylation stabilizes OsALDH2B1 under stress, establishing a signaling axis that overcomes growth‐defense trade‐offs and provides a direct target for breeding high‐yield, alkaline ...
Zemin Ma   +13 more
wiley   +1 more source

Effect of histone deacetylase and proteasome inhibitors in glioma models

open access: green
Luciana; id_orcid 0000-0002-2306-7959 Costa Furtado   +2 more
openalex   +1 more source

Epigenetic Regulation in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch   +3 more
wiley   +1 more source

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