Results 171 to 180 of about 197,157 (312)

Renal cell carcinoma with atypical omental metastasis: A case report and literature review

UroPrecision, EarlyView.
Abstract Background Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults, with common metastatic sites including the lungs, bones, liver, and brain. Omental metastasis is exceedingly rare and usually occurs postoperatively. Fumarate hydratase‐deficient (FH‐deficient) RCC, a recently classified and highly aggressive subtype of ...
Andrew Jing, Zachary Guo, Katherine Wu, Wei Wang, James Jing   +4 more
wiley   +1 more source

Small molecule KDM4s inhibitors as anti-cancer agents

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Histone demethylation is a vital process in epigenetic regulation of gene expression. A number of histone demethylases are present to control the methylated states of histone.
Hongzhi Lin, Qihang Li, Qi Li, Jie Zhu, Kai Gu, Xueyang Jiang, Qianqian Hu, Feng Feng, Wei Qu, Yao Chen, Haopeng Sun   +10 more
doaj   +1 more source

Data from Inhibition of the Histone H3K27 Demethylase UTX Enhances Tumor Cell Radiosensitivity

, 2023
Barbara H. Rath, Isabella Waung, Kevin Camphausen, Philip J. Tofilon   +3 more
openalex   +1 more source

Application of 23Na MRI at 7 Tesla in distinguishing IDH genotype, P53 phenotype, and Ki‐67 LI in adult‐type diffuse gliomas

VIEW, EarlyView.
Notes: Their molecular characteristics—such as IDH genotype, P53 phenotype, and Ki‐67 labeling index—are critical determinants of treatment strategies and prognosis for patients of adult‐type diffuse gliomas. In this study, we employed 7‐tesla sodium magnetic resonance imaging (23Na MRI) and demonstrated that total sodium concentration (TSC) and ...
Letian Yuan, Chaofei He, Xiaoxiao Ma, Guoli Liu, Xiangbing Bian, Song Wang, Sisi Li, Jianxun Qu, Caohui Duan, Xin Lou   +9 more
wiley   +1 more source

Epigenetics and Breast Cancers

Obstetrics and Gynecology International, 2012
Several of the active compounds in foods, poisons, drugs, and industrial chemicals may, by epigenetic mechanisms, increase or decrease the risk of breast cancers.
An T. Vo, Richard M. Millis
doaj   +1 more source

JmjC Family of Histone Demethylases Form Nuclear Condensates. [PDF]

Int J Mol Sci, 2022
Vicioso-Mantis M, Aguirre S, Martínez-Balbás MA.   +2 more
europepmc   +1 more source

Correction: Histone Demethylase JMJD1A Promotes Tumor Progression via Activating Snail in Prostate Cancer [PDF]

, 2022
Donge Tang, Yong Dai, Songhui Xu
openalex   +1 more source

Exploring the impact of microbial dysbiosis on ovarian cancer and the therapeutic potential of probiotics

VIEW, EarlyView.
Ovarian cancer has been linked to the microbiome as a potential environmental contributor, but how this association relates to tumor progression remains unclear. By comparing tumor and nontumor tissues, we identified a severity‐associated microbial and metabolic signature and showed that probiotics can partially restore immune balance and slow tumor ...
Chanyuan Li, Nalan Tu, Xin Ning, Yunyan Cong, Fei Wu, Xiuli Zhang, Runrong Li, Yue Xu, Binqiao Wang, Liqin Jin, Yuanming Shen, Jihong Liu   +11 more
wiley   +1 more source

Catalysis by KDM6 Histone Demethylases - A Synergy between the Non-Heme Iron(II) Center, Second Coordination Sphere, and Long-Range Interactions. [PDF]

Chemistry, 2023
Rifayee SBJS, Chaturvedi SS, Warner C, Wildey J, White W, Thompson M, Schofield CJ, Christov CZ.   +7 more
europepmc   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source