Results 151 to 160 of about 19,208 (197)

JARID1 Histone Demethylases: Emerging Targets in Cancer. [PDF]

Trends Cancer, 2017
Harmeyer KM, Facompre ND, Herlyn M, Basu D.   +3 more
europepmc   +1 more source

Targeting of Histone Demethylases KDM5A and KDM6B Inhibits the Proliferation of Temozolomide-Resistant Glioblastoma Cells. [PDF]

Cancers (Basel), 2019
Romani M, Daga A, Forlani A, Pistillo MP, Banelli B.   +4 more
europepmc   +1 more source

Histone demethylases control root elongation in response to stress-signaling hormone abscisic acid. [PDF]

Plant Signal Behav, 2019
Wu J, Yamaguchi N, Ito T.
europepmc   +1 more source

KDM5 histone demethylases repress immune response via suppression of STING. [PDF]

PLoS Biol, 2018
Wu L, Cao J, Cai WL, Lang SM, Horton JR, Jansen DJ, Liu ZZ, Chen JF, Zhang M, Mott BT, Pohida K, Rai G, Kales SC, Henderson MJ, Hu X, Jadhav A, Maloney DJ, Simeonov A, Zhu S, Iwasaki A, Hall MD, Cheng X, Shadel GS, Yan Q.   +23 more
europepmc   +1 more source

Crosstalk between epigenetics and metabolism-Yin and Yang of histone demethylases and methyltransferases in cancer. [PDF]

Brief Funct Genomics, 2017
Filipp FV.
europepmc   +1 more source

The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance.

Blood, 2019
Agger K, Nishimura K, Miyagi S, Messling JE, Rasmussen KD, Helin K.   +5 more
europepmc   +1 more source

Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B. [PDF]

Molecules, 2019
Pippa S, Mannironi C, Licursi V, Bombardi L, Colotti G, Cundari E, Mollica A, Coluccia A, Naccarato V, La Regina G, Silvestri R, Negri R.   +11 more
europepmc   +1 more source

Cooperation between ETS variant 2 and Jumonji domain‑containing 2 histone demethylases. [PDF]

Mol Med Rep, 2018
Li X, Moon G, Shin S, Zhang B, Janknecht R.   +4 more
europepmc   +1 more source

Role of Histone Demethylases in Cardiomyocytes Induced to Hypertrophy. [PDF]

Biomed Res Int, 2016
Rosales W, Carulla J, García J, Vargas D, Lizcano F.   +4 more
europepmc   +1 more source

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Inhibitors of histone demethylases

Bioorganic and Medicinal Chemistry, 2011
Methylated lysines are important epigenetic marks. The enzymes involved in demethylation have recently been discovered and found to be involved in cancer development and progression. Despite the relative recent discovery of these enzymes a number of inhibitors have already appeared.
Rasmus Prætorius Clausen, Michael Gajhede, Jesper Langgaard Kristensen   +2 more
exaly   +4 more sources