Results 161 to 170 of about 181,554 (237)

Single-Molecule Tracking dataset for histone H3 (hht1) from live and fixed cells of Schizosaccharomyces pombe. [PDF]

Sci Data
Kumari A, Podh NK, Sen S, Kashyap K, Islam S, Gupta A, Rajakumara E, Nambiar M, Mehta G.   +8 more
europepmc   +1 more source

Cryo-EM and biochemical analyses of the nucleosome containing the human histone H3 variant H3.8. [PDF]

J Biochem, 2023
Hirai S, Kujirai T, Akatsu M, Ogasawara M, Ehara H, Sekine SI, Ohkawa Y, Takizawa Y, Kurumizaka H.   +8 more
europepmc   +1 more source

Echinococcus granulosus antigen B regulates T‐cell function through inhibition of signal transducer and activator of transcription 3 in experimental immune thrombocytopenia

British Journal of Haematology, EarlyView.
During the pathological process of immune thrombocytopenia, signal transducer and activator of transcription 3 (STAT3) is activated by JAKs, leading to the production of a large number of inflammatory cytokines and promoting the activation of Th1, Th2 and Th17 cells.
Yingbin Yue, Yunfei Zhang, Yongfeng Cheng, Hongjie Jiao, Mei Yan   +4 more
wiley   +1 more source

4-Hexylresorcinol Enhances Glut4 Expression and Glucose Homeostasis via AMPK Activation and Histone H3 Acetylation. [PDF]

Int J Mol Sci
Che X, Oh JH, Kang YJ, Kim DW, Kim SG, Choi JY, Garagiola U.   +6 more
europepmc   +1 more source

Identification of a Distal Enhancer That Regulates TGF‐β–Induced SNAI1 Expression

Cancer Science, EarlyView.
In TGF‐β–stimulated cells, the activated Smad complex composed of Smad3 and Smad4 associates with the distal super enhancer region 2 (DSE2) and enhances its interaction with the SNAI1 proximal promoter, thus inducing SNAI1 expression. RREB1 regulates the basal activity of the enhancer but not its inducibility by TGF‐β.
Hao Fu, Yuka Itoh, Tomoe Sawaguchi, Shigeo Otake, Chiho Omata, Masao Saitoh, Keiji Miyazawa   +6 more
wiley   +1 more source

Effects of treadmill running on anxiety- and craniofacial pain-like behaviors with histone H3 acetylation in the brain of mice subjected to social defeat stress. [PDF]

PLoS One
Piriyaprasath K, Hasegawa M, Iwamoto Y, Kamimura R, Yusuf ASH, Fujii N, Yamamura K, Okamoto K.   +7 more
europepmc   +1 more source

The Role of Histone Methyltransferase SETDB1 in Normal and Malignant Hematopoiesis

Cancer Science, EarlyView.
In this review, we discuss the role of SETDB1 in gene regulation, including an overview of its structural features and key cofactors. We also highlight the lineage‐specific roles of SETDB1 in both normal hematopoietic processes and hematological malignancies, emphasizing its function as an immune checkpoint molecule that suppresses natural killer cell ...
Yu‐Hsuan Chang, Susumu Goyama
wiley   +1 more source

MUSTN1 Interaction With SMPX Regulates Muscle Development and Regeneration

Cell Proliferation, EarlyView.
Model of the role of MUSTN1 in skeletal muscle development. MUSTN1‐KO mice display delayed muscle growth and regeneration. MUSTN1 protects SMPX from instability and maintains the morphology of muscle fibres. MUSTN1 and SMPX synergistically promote myoblast proliferation and dependently facilitate differentiation.
Yu Fu, Xin Hao, Peng Shang, Jingru Nie, Yangzom Chamba, Bo Zhang, Hao Zhang   +6 more
wiley   +1 more source

Trapping of yFACT at 3' ends of genes is not a universal characteristic of yeast versions of Bryant-Li-Bhoj syndrome histone H3 mutants. [PDF]

MicroPubl Biol
Beard JS, Francis LK, Forrest RC, Kalinowski A, Parks JC, Griffin WH, Tackett CL, Duina AA.   +7 more
europepmc   +1 more source

Tryptophan Metabolic Enzyme IL4I1 Inhibits Ferroptosis by Decreasing Ubiquitination of Nrf2 via I3P in Glioblastoma

Cell Proliferation, EarlyView.
Interleukin 4‐induced 1 (IL4I1) is a novel anti‐ferroptosis regulator‐IL4I1 by regulating Nrf2 and serving as a ROS scavenger in glioblastoma multiforme (GBM). In addition, the ubiquitination of Nrf2 could be attenuate by indole‐3‐pyruvic acid binding with Nrf2 directly.
Yang Xu, Yu Hong, Tengfeng Yan, Qian Sun, Fanen Yuan, Shanwen Liang, Liguo Ye, Rongxin Geng, Yangzhi Qi, Qingsong Ye, Qianxue Chen   +10 more
wiley   +1 more source