Results 251 to 260 of about 196,399 (287)

Novel Nitrogen Heterocycle-Hydroxamic Acid Conjugates Demonstrating Potent Anti-Acute Lymphoblastic Leukemia Activity: Induction of Endogenous Apoptosis and G0/G1 Arrest via Regulation of Histone H3 Acetylation and AKT Phosphorylation in Jurkat Cells. [PDF]

Cells
Wu L, Zhao L, Wang L, Lu Y, Lou G, Zhang B, Wang N.   +6 more
europepmc   +1 more source

An RNA interference biopesticide reduces reproduction of the honey bee parasite Varroa destructor by down‐regulating embryo development pathways

Pest Management Science, EarlyView.
Varroa destructor mites exposed to dsRNA specific in sequence to a V. destructor calmodulin gene significantly effected gene expression of adult female mites sampled 5 days after entering a honey bee brood cell to reproduce. Significantly down‐regulated genes included Calmodulin and were associated with calcium ion binding and embryo developmental ...
Zoe E Smeele, Rose A McGruddy, James W Baty, Brian Manley, Kenneth Narva, Emma De Neef, Eric RL Gordon, Upendra K Devisetty, Katie Youngs, Antoine Felden, Philip J Lester   +10 more
wiley   +1 more source

Biomolecular tracking by FIRESCAPE reveals distinct modes of clearance, damage induction and cellular uptake for extracellular histone H3

Josephson B, Poh AWJ, Demyanenko Y, Yates AG, Ford J, Giltrap AM, Auchynnikava T, Tan KV, Dunstan IK, Liu W, Cribbs AP, Wang C, Philpott M, Able S, Sap JBI, Bedwell A, Aarnio R, Dickens AM, Helin JS, Kovacs L, Rajala NA, Miner MWG, Oppermann U, Vallis KA, McGowan DR, Airaksinen AJ, Gouverneur V, Mohammed S, Anthony DC, Davis BG.   +29 more
europepmc   +1 more source

A two-step regulatory mechanism dynamically controls histone H3 acetylation by SAGA complex at growth-related promoters. [PDF]

Nucleic Acids Res
Zencir S, Dilg D, Bruzzone MJ, Stutz F, Soudet J, Shore D, Albert B.   +6 more
europepmc   +1 more source

Evaluation of electrolyzed water to control fungal trunk pathogens in grapevine nurseries

Pest Management Science, Volume 81, Issue 4, Page 1740-1751, April 2025.
Electrolyzed water treatments could have promising applications in the grapevine nursery process to prevent or reduce infections caused by fungal trunk pathogens on grapevine propagation material. Abstract BACKGROUND Grapevine producers demand solutions to control fungal trunk pathogens (FTPs) in nurseries.
Mónica Berbegal, Adolfo Blasco, Grégoire Gaume, Pedro Amorós, Antônia Fernandes, José V. Ros‐Lis, Josep Armengol   +6 more
wiley   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian, Lena Palaniyappan, Theodore T. Kolivakis, Howard C. Margolese   +3 more
wiley   +1 more source

Transcription factor ATF3 aggravates kidney fibrosis by maintaining the state of histone H3 lysine 27 acetylation. [PDF]

Chin Med J (Engl)
Yang L, Chen Y, Guo F, Wang B, Ying Z, Kuang Y, Zeng X, Ma L, Yu H, Fu P.   +9 more
europepmc   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for WHO CNS5 adult‐type diffuse gliomas

Brain Pathology, EarlyView.
ADAPTR recommendations for Adult‐type Diffuse Gliomas in Resource‐restrained settings. Abstract The fifth edition of the WHO classification of CNS Tumors (WHO CNS5) has revised the diagnostic and grading criteria for Adult‐type Diffuse Gliomas (ADGs) by integrating molecular parameters with histologic features.
Vani Santosh, Chitra Sarkar, Shilpa Rao, Ho‐Keung Ng, Junji Shibahara, Maysa Al‐Hussaini, Michael E. Buckland, Sung‐Hye Park, Tarik Tihan, Pieter Wesseling, David N. Louis, Takashi Komori   +11 more
wiley   +1 more source

NONO interacts with nuclear PKM2 and directs histone H3 phosphorylation to promote triple-negative breast cancer metastasis. [PDF]

J Exp Clin Cancer Res
Li Q, Ci H, Zhao P, Yang D, Zou Y, Chen P, Wu D, Shangguan W, Li W, Meng X, Xing M, Chen Y, Zhang M, Chen B, Kong L, Zen K, Huang DCS, Jiang ZW, Zhao Q.   +18 more
europepmc   +1 more source