Results 211 to 220 of about 166,151 (260)

Histone Methylation-Mediated Reproductive Toxicity to Consumer Product Chemicals in Caenorhabditis elegans: An Epigenetic Adverse Outcome Pathway (AOP). [PDF]

Environ Sci Technol
Kim J, Choi J.
europepmc   +1 more source

KMT5C‐Mediated H4K20me3 Recruits EWSR1 to Propel Clear Cell Renal Cell Carcinoma Progression via Regulating ACADM Transcription and m6A Modification

Med Research, EarlyView.
A schematic diagram illustrating the KMT5C‐H4K20me3‐EWSR1‐ACADM signaling axis and its role in ccRCC progression. Key Outcomes: KMT5C/H4K20me3 are upregulated in ccRCC and predict poor prognosis. EWSR1 is a novel noncanonical H4K20me3 reader in ccRCC. KMT5C/EWSR1 co‐repress ACADM via transcription and m6A modification. A‐196 + sunitinib synergistically
Chengjian Ji, Da Zhong, Tian Rao, Xiaojun Li, Weiyu Kong, Xi Zhang, Xiyi Wei, Bing Yao, Xinqiang Li, Ninghong Song, Chao Qin   +10 more
wiley   +1 more source

Mechanisms of action and resistance in histone methylation-targeted therapy. [PDF]

Nature
Yamagishi M, Kuze Y, Kobayashi S, Nakashima M, Morishima S, Kawamata T, Makiyama J, Suzuki K, Seki M, Abe K, Imamura K, Watanabe E, Tsuchiya K, Yasumatsu I, Takayama G, Hizukuri Y, Ito K, Taira Y, Nannya Y, Tojo A, Watanabe T, Tsutsumi S, Suzuki Y, Uchimaru K.   +23 more
europepmc   +1 more source

Endurance exercise-induced histone methylation modification involved in skeletal muscle fiber type transition and mitochondrial biogenesis. [PDF]

Sci Rep
Li J, Zhang S, Li C, Zhang X, Shan Y, Zhang Z, Bo H, Zhang Y.   +7 more
europepmc   +1 more source

A Histone Methylation-MAPK Signaling Axis Drives Durable Epithelial-Mesenchymal Transition in Hypoxic Pancreatic Cancer. [PDF]

Cancer Res
Brown BA, Myers PJ, Adair SJ, Pitarresi JR, Sah-Teli SK, Campbell LA, Hart WS, Barbeau MC, Leong K, Seyler N, Kane W, Lee KE, Stelow E, Jones M, Simon MC, Koivunen P, Bauer TW, Stanger BZ, Lazzara MJ.   +18 more
europepmc   +1 more source

Long noncoding RNA hottip maintained skeletal homeostasis <i>via</i> suppressing the enhancer of zeste homolog 2 (Ezh2)/histone methylation regulatory axis. [PDF]

Noncoding RNA Res
Li ZP, Mai YX, Zhou ST, Shi CJ, Shao J, Liang PP, Liang WC, Zhang JF.   +7 more
europepmc   +1 more source

A Drosophila screen identifies a role for histone methylation in ER stress preconditioning. [PDF]

G3 (Bethesda)
Owings KG, Chow CY.
europepmc   +1 more source

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Histone Methylation in Higher Plants

Annual Review of Plant Biology, 2010
Histone methylation plays a fundamental role in regulating diverse developmental processes and is also involved in silencing repetitive sequences in order to maintain genome stability. The methylation marks are written on lysine or arginine by distinct enzymes, namely, histone lysine methyltransferases (HKMTs) or protein arginine methyltransferases ...
Xiaofeng Cao, Xia Cui, Chunyan Liu
exaly   +3 more sources

Epigenetic regulation: methylation of histone and non-histone proteins

Science in China Series C: Life Sciences, 2009
Histone methylation is believed to play important roles in epigenetic memory in various biological processes. However, questions like whether the methylation marks themselves are faithfully transmitted into daughter cells and through what mechanisms are currently under active investigation. Previously, methylation was considered to be irreversible, but
Fei Lan, Lan Fei
exaly   +3 more sources

Enzymatic methylation of histones

Archives of Biochemistry and Biophysics, 1969
Abstract Various proteins were methylated by purified protein methylase I. Since the enzyme also methylates its endogenous histones, detailed studies on the protein methylation by the purified protein methylase I were carried out with added histone. Exogenous histone methylated enzymatically gave rise to guanidyl-methylated and α-N-methyl, guanidyl ...
W K, Paik, S, Kim
openaire   +2 more sources