Results 131 to 140 of about 186,634 (241)

nuMap: A Web Platform for Accurate Prediction of Nucleosome Positioning

Genomics, Proteomics & Bioinformatics, 2014
Nucleosome positioning is critical for gene expression and of major biological interest. The high cost of experimentally mapping nucleosomal arrangement signifies the need for computational approaches to predict nucleosome positions at high resolution ...
Bader A. Alharbi, Thamir H. Alshammari, Nathan L. Felton, Victor B. Zhurkin, Feng Cui   +4 more
doaj   +1 more source

Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF. [PDF]

Sci Adv, 2022
Corbeski I, Guo X, Eckhardt BV, Fasci D, Wiegant W, Graewert MA, Vreeken K, Wienk H, Svergun DI, Heck AJR, van Attikum H, Boelens R, Sixma TK, Mattiroli F, van Ingen H.   +14 more
europepmc   +1 more source

Ion counting demonstrates a high electrostatic field generated by the nucleosome

eLife, 2019
In eukaryotes, a first step towards the nuclear DNA compaction process is the formation of a nucleosome, which is comprised of negatively charged DNA wrapped around a positively charged histone protein octamer.
Magdalena Gebala, Stephanie L Johnson, Geeta J Narlikar, Dan Herschlag   +3 more
doaj   +1 more source

Differential Salt Fractionation of Nuclei to Analyze Chromatin-associated Proteins from Cultured Mammalian Cells

Bio-Protocol, 2017
Nucleosomes are the core units of cellular chromatin and are comprised of 147 base pairs (bp) of DNA wrapped around an octamer of histone proteins. Proteins such as chromatin remodelers, transcription factors, and DNA repair proteins interact dynamically
Christin Herrmann, Daphne Avgousti, Matthew Weitzman   +2 more
doaj   +1 more source

Chromatin is an ancient innovation conserved between Archaea and Eukarya

eLife, 2012
The eukaryotic nucleosome is the fundamental unit of chromatin, comprising a protein octamer that wraps ∼147 bp of DNA and has essential roles in DNA compaction, replication and gene expression. Nucleosomes and chromatin have historically been considered
Ron Ammar, Dax Torti, Kyle Tsui, Marinella Gebbia, Tanja Durbic, Gary D Bader, Guri Giaever, Corey Nislow   +7 more
doaj   +1 more source

Targeting and regulatory mechanisms in chromosome-wide gene regulation using Drosophila melanogaster as a model organism [PDF]

, 2010
Tese de mestrado. Biologia (Biologia Molecular e Genética). Universidade de Lisboa, Faculdade de Ciências, 2010O cromossoma 4 de Drosophila melanogaster é muito heterocromático, sendo rico em DNA satélite e DNA de elementos transposáveis. Apesar das suas
Figueiredo, Ana Margarida Adónis, 1986-
core  

In vivo assembly of complete eukaryotic nucleosomes and (H3-H4)-only non-canonical nucleosomal particles in the model bacterium Escherichia coli

Communications Biology
As a fundamental unit for packaging genomic DNA into chromatin, the eukaryotic nucleosome core comprises a canonical octamer with two copies for each histone, H2A, H2B, H3, and H4, wrapped around with 147 base pairs of DNA.
Xiaojuan Zhou, Niubing Zhang, Jie Gong, Kaixiang Zhang, Ping Chen, Xiang Cheng, Bang-Ce Ye, Guoping Zhao, Xinyun Jing, Xuan Li   +9 more
doaj   +1 more source

XL-MS and Native MS data for "Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF"

, 2022
Domenico Fasci, Albert J. R. Heck
openalex   +1 more source

The reconstitution of the histone octamer

, 1987
This thesis describes methodology for the reconstitution of the chicken erythrocyte octamer from acid-denatured histones or the natural H3-H4 tetramer and H2A-H2B dimers. Oligomeric properties of reconstituted octamers were elucidated during column chromatographic and chemical cross-linking studies.
openaire   +1 more source

An octamer of histones H3 and 114 forms a compact complex with DNA of nucleosome size

, 1978
Richard H. Simon, R. Daniel Camerini‐Otero, Gary Felsenfeld   +2 more
openalex   +2 more sources