High-resolution structure of the native histone octamer. [PDF]
Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2005 Crystals of native histone octamers (H2A-H2B)-(H4-H3)-(H3'-H4')-(H2B'-H2A') from chick erythrocytes in 2 M KCl, 1.35 M potassium phosphate pH 6.9 diffract X-rays to 1.90 A resolution, yielding a structure with an R(work) value of 18.7% and an Rfree of 22.
C. Wood +5 more
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Unique yeast histone sequences influence octamer and nucleosome stability
FEBS Letters, 2016 Yeast nucleosomes are known to be intrinsically less stable than those from higher eukaryotes. This difference presents significant challenges for the production of yeast nucleosome core particles (NCPs) and chromatin for in vitro analyses. Using recombinant yeast, human, and chimeric histone proteins, we demonstrate that three divergent amino acids in
A. Leung +5 more
semanticscholar +3 more sources
A New Fluorescence Resonance Energy Transfer Approach Demonstrates That the Histone Variant H2AZ Stabilizes the Histone Octamer within the Nucleosome [PDF]
Journal of Biological Chemistry, 2004 Nucleosomes are highly dynamic macromolecular complexes that are assembled and disassembled in a modular fashion. One important way in which this dynamic process can be modulated is by the replacement of major histones with their variants, thereby ...
Young‐Jun Park +3 more
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Journal of Biological Chemistry, 2000 Replication of chromosomal templates requires the passage of the replication machinery through nucleosomally organized DNA. To gain further insights into these processes we have used chromatin that was reconstituted with dimethyl suberimidate-cross ...
Birgit Vestner +2 more
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One-pot refolding of core histones from bacterial inclusion bodies allows rapid reconstitution of histone octamer. [PDF]
Protein Expr Purif, 2015 Lee YT +4 more
europepmc +2 more sources
Structural DNMT-nucleosome contacts are related to DNA methylation patterns [PDF]
Epigenetics & ChromatinDNA-methylation is a key epigenetic mark in chromatin that attenuates chromatin accessibility during transcription, implying a crucial role in gene regulation.
Kevin George +4 more
doaj +2 more sources
Histone octamer trans-transfer: a signature mechanism of ATP-dependent chromatin remodelling unravelled in wheat nuclear extract [PDF]
Annals of Botany, 2011 Vishal V. Raut +2 more
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Histone octamer function in vivo : mutations in the dimer-tetramer interfaces disrupt both gene activation and repression [PDF]
EMBO Journal, 1997 Maria Santisteban +3 more
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Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State [PDF]
Molecules and Cells, 2010 Peter J. Skene +7 more
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Lysine‐containing DNA‐binding regions on the surface of the histone octamer in the nucleosome core particle [PDF]
European Journal of Biochemistry, 1986 Sarah F. Lambert, Jean Thomas
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