Results 181 to 190 of about 149,566 (304)

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Nonchromatin regulatory functions of the histone variant H2A.B in SWI/SNF genomic deposition. [PDF]

Sci Adv
Jiang X, Wen J, Nelson ML, Dijkwel Y, Cairns B, Bauer UM, Hart-Smith G, Soboleva TA, Tremethick DJ.   +8 more
europepmc   +1 more source

Linker histone variant H1.2 is a brake on white adipose tissue browning. [PDF]

Nat Commun, 2023
Yuan Y, Fan Y, Zhou Y, Qiu R, Kang W, Liu Y, Chen Y, Wang C, Shi J, Liu C, Li Y, Wu M, Huang K, Liu Y, Zheng L.   +14 more
europepmc   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

Histone variant H2A.Z cooperates with EBNA1 to maintain Epstein-Barr virus latent epigenome. [PDF]

mBio
Castro-Muñoz LJ, Maestri D, Yoon L, Karisetty BC, Tempera I, Lieberman P.   +5 more
europepmc   +1 more source

Histone variant-specific post-translational modifications. [PDF]

Semin Cell Dev Biol, 2023
Joseph FM, Young NL.
europepmc   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Structural basis of RNAPII transcription on the nucleosome containing histone variant H2A.B. [PDF]

EMBO J
Akatsu M, Hirano R, Kujirai T, Ogasawara M, Ehara H, Sekine SI, Takizawa Y, Kurumizaka H.   +7 more
europepmc   +1 more source

Histone variant H2B.Z acetylation is necessary for maintenance of Toxoplasma gondii biological fitness. [PDF]

Biochim Biophys Acta Gene Regul Mech, 2023
Vanagas L, Muñoz D, Cristaldi C, Ganuza A, Nájera R, Bonardi MC, Turowski VR, Guzman F, Deng B, Kim K, Sullivan WJ, Angel SO.   +11 more
europepmc   +1 more source

Remote Modulation of Single‐Atom Catalyst Boosts High‐Valent Cobalt–Oxo Species Generation for Water Purification and Detoxification

Advanced Science, EarlyView.
This study develops a phosphorus‐doped cobalt single‐atom catalyst that enhances high‐valent cobalt–oxo species generation for water purification. This atomic‐level tuning boosts the catalyst's activity by 3.5 times, enabling efficient pollutant degradation. A continuous‐flow reactor achieves high, long‐term removal efficiency, producing water with low
Wen‐Min Wang, Zheng‐Wei Yang, De‐Xiu Wu, Wen‐Long Wang, Qian‐Yuan Wu   +4 more
wiley   +1 more source