Results 41 to 50 of about 1,411,447 (295)
Management of functional neurological disorder. [PDF]
, 2020 Functional neurological disorder (FND) is a common cause of persistent and disabling neurological symptoms. These symptoms are varied and include abnormal control of movement, episodes of altered awareness resembling epileptic seizures and abnormal ...
Coebergh, JA +7 more
core +1 more source
Similar yet Critically Different: The distribution, dynamics and function of Histone Variants.
Journal of Experimental Botany, 2020 Organization of the genetic information into chromatin plays an important role in the regulation of all DNA template-based reactions. The incorporation of different variant versions of the core histones H3, H2A and H2B or the linker histone H1 results in
A. Probst, B. Desvoyes, C. Gutiérrez
semanticscholar +1 more source
Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer
Nature Communications, 2017 Acetylation of the histone variant H2A.Z at gene promoters is associated with oncogene activation; however, it is unclear if such modification has a role in regulating the function of enhancers.
Fátima Valdés-Mora +18 more
doaj +1 more source
Extracting histones for the specific purpose of label-free MS [PDF]
, 2016 Extracting histones from cells is the first step in studies that aim to characterize histones and their post-translational modifications (hPTMs) with MS.
De Clerck, Laura +9 more
core +2 more sources
The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken [PDF]
, 2005 The replacement histone H2A.Z is variously reported as being linked to gene expression and preventing the spread of heterochromatin in yeast, or concentrated at heterochromatin in mammals.
Bonifer, C. +8 more
core +5 more sources
The evolution and functional divergence of the histone H2B family in plants.
PLoS Genetics, 2020 Chromatin regulation of eukaryotic genomes depends on the formation of nucleosome complexes between histone proteins and DNA. Histone variants, which are diversified by sequence or expression pattern, can profoundly alter chromatin properties.
Danhua Jiang +7 more
doaj +1 more source
Epigenetic aberrations and cancer [PDF]
, 2006 The correlation between epigenetic aberrations and disease underscores the importance of epigenetic mechanisms.
Brown, Mark A., Ducasse, Miryam
core +3 more sources
Histone Variants in Metazoan Development [PDF]
Developmental Cell, 2010 Embryonic development is regulated by both genetic and epigenetic mechanisms, with nearly all DNA-templated processes influenced by chromatin architecture. Sequence variations in histone proteins, core components of chromatin, provide a means to generate diversity in the chromatin structure, resulting in distinct and profound biological outcomes in the
Banaszynski, Laura A. +2 more
openaire +2 more sources
BMC Plant Biology, 2009 Background Histone modifications and histone variants are of importance in many biological processes. To understand the biological functions of the global dynamics of histone modifications and histone variants in higher plants, we elucidated the variants
Lam Hon-Ming +6 more
doaj +1 more source
Functionally Annotating Regulatory Elements in the Equine Genome Using Histone Mark ChIP-Seq. [PDF]
, 2019 One of the primary aims of the Functional Annotation of ANimal Genomes (FAANG) initiative is to characterize tissue-specific regulation within animal genomes.
Bellone, Rebecca R +9 more
core +2 more sources