Results 241 to 250 of about 394,873 (373)

SCRIPT: Predicting Single‐Cell Long‐Range Cis‐Regulation Based on Pretrained Graph Attention Networks

Advanced Science, EarlyView.
SCRIPT is a novel method inferring single‐cell cis‐regulatory relationships (CRRs) from transcriptomic and chromatin accessibility data. SCRIPT incorporates two key innovations: graph causal attention networks supported by empirical CRR evidence, and representation learning enhanced through pretraining on atlas‐scale single‐cell data.
Yu Zhang, Baole Wen, Yifeng Jiao, Yuchen Liu, Xin Guo, Yushuai Wu, Jiyang Li, Limei Han, Yinghui Xu, Xin Gao, Yuan Qi, Yuan Cheng, Ying He, Weidong Tian   +13 more
wiley   +1 more source

Insights into the synchronization between DNA replication and parental histone recycling. [PDF]

Biochem Soc Trans
Tang X, Yao Y, Li G, Gan H.
europepmc   +1 more source

HISTONE CONTENT OF CHROMOSOMAL LOCI ACTIVE AND INACTIVE IN RNA SYNTHESIS [PDF]

, 1967
Martin A. Gorovsky, John Woodard
openalex   +1 more source

A new method for studying histone‐histone interactions [PDF]

FEBS Letters, 1975
S. Forrester, E.W. Johns
openaire   +3 more sources

Pathogenicity of Mediator Complex Subunit 27 (MED27) in a Neurodevelopmental Disorder with Cerebellar Atrophy

Advanced Science, EarlyView.
MED27 is one of the 26 subunits in the human Mediator complex (MED). Neurodevelopmental disorder‐causing MED27 genetic variants induce instability of MED, leading to disrupted DNA occupancy, altered chromatin interaction, and subsequent transcriptional dysregulation of critical downstream genes, including master regulatory transcription factors ...
Nuermila Yiliyaer, Xiaocheng Li, Tianyu Guo, Haiying Zhou, Lihai Gong, Luowei Yuan, Yang Fu, Yulong Qiao, Ying Lam Lui, Nuo Chen, Pengfei Lin, Hoi Hung Cheung, Ho Ko, Linyan Meng, Xiao Chen, Yong Lei, Kin Ming Kwan, Huating Wang, Shen Gu   +18 more
wiley   +1 more source

News and views: lysine sorbylation enters the expanding universe of posttranslational modifications. [PDF]

Arch Toxicol
Ashry R, Krämer OH.
europepmc   +1 more source

Metabolism of Histones of Brain and Liver

, 1966
R. S. Piha, Michel Cuénod, Heinrich Waelsch   +2 more
openalex   +1 more source

Compilation analysis of histones and histone genes

Nucleic Acids Research, 1986
openaire   +4 more sources

Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4.

Blood, 2011
F. Semeraro, C. Ammollo, J. Morrissey, G. Dale, P. Friese, N. Esmon, C. Esmon   +6 more
semanticscholar   +1 more source

BLOC1S1 Attenuates B. Melitensis 16M LPS‐Triggered Autophagy by Spatial Confinement of TDP‐43

Advanced Science, EarlyView.
This study explores how B. melitensis 16M LPS and BLOC1S1 regulate autophagy in goat spermatogonial stem cells. The 16M LPS is activating AMPK‐dependent autophagy, increasing LC3B‐II/I ratios and lysosomal genes, while Escherichia coli LPS shows no effect.
Shicheng Wan, Miao Han, Mengfei Zhang, Wenbo Chen, Fangde Xie, Xuan Luo, Wenping Wu, Congliang Wang, Donghui Yang, Bin Han, Haijing Zhu, Haisheng Yu, Na Li, Jinlian Hua   +13 more
wiley   +1 more source