Results 261 to 270 of about 138,386 (301)
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Journal of Molecular Evolution, 1978
The amino acid sequences of bovine histones H2A, H2B, H3, and H4 and the first 107 residues of rabbit thymus histone H1 were examined using newly developed procedures designed to detect and evaluate weak similarities (de Haën et al., 1976). Using the McLachlan scoring system, regions of statistically significant similarity were found between several ...
G R, Reeck, E, Swanson, D C, Teller
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The amino acid sequences of bovine histones H2A, H2B, H3, and H4 and the first 107 residues of rabbit thymus histone H1 were examined using newly developed procedures designed to detect and evaluate weak similarities (de Haën et al., 1976). Using the McLachlan scoring system, regions of statistically significant similarity were found between several ...
G R, Reeck, E, Swanson, D C, Teller
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The International Journal of Biochemistry & Cell Biology, 1997
Linker histones of which histone H1 is a representative are a diverse family of architectural proteins within the eukaryotic nucleus. These proteins have a variety of structures, but invariably contain a region enriched in lysine, serine, alanine and proline.
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Linker histones of which histone H1 is a representative are a diverse family of architectural proteins within the eukaryotic nucleus. These proteins have a variety of structures, but invariably contain a region enriched in lysine, serine, alanine and proline.
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Current Opinion in Pharmacology, 2003
Post-translational modification of the histones of chromatin has a fundamental role in regulating gene expression. Enzymes involved in these epigenetic events include histone deacetylases (class I and class II), which can be inhibited by a structurally diverse group of small molecules.
Paul A, Marks +2 more
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Post-translational modification of the histones of chromatin has a fundamental role in regulating gene expression. Enzymes involved in these epigenetic events include histone deacetylases (class I and class II), which can be inhibited by a structurally diverse group of small molecules.
Paul A, Marks +2 more
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Experimental Cell Research, 1967
Abstract The meiotic cells in the anthers of lily and tulip contain a unique histone which is absent or nearly so, from the somatic tissues of these plants. This histone, termed the meiotic histone, is synthesized during the premeiotic histone synthesis, persists through meiosis, microsporogenesis, and pollen maturation.
W F, Sheridan, H, Stern
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Abstract The meiotic cells in the anthers of lily and tulip contain a unique histone which is absent or nearly so, from the somatic tissues of these plants. This histone, termed the meiotic histone, is synthesized during the premeiotic histone synthesis, persists through meiosis, microsporogenesis, and pollen maturation.
W F, Sheridan, H, Stern
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Life Sciences, 1974
Abstract The biological roles of the histones are multiple; by complexing to DNA they cause such DNA to be inactive as a template for RNA polymerase; they cause supercoiling of the DNA which would appear to be a fundamental requirement for further orders of supercoiling, presumable exemplified by metaphase chromosomes; a particular histone even forms
J, Bonner, W T, Garrard
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Abstract The biological roles of the histones are multiple; by complexing to DNA they cause such DNA to be inactive as a template for RNA polymerase; they cause supercoiling of the DNA which would appear to be a fundamental requirement for further orders of supercoiling, presumable exemplified by metaphase chromosomes; a particular histone even forms
J, Bonner, W T, Garrard
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Annual Review of Biochemistry, 2001
▪ Abstract Transcriptional regulation in eukaryotes occurs within a chromatin setting and is strongly influenced by nucleosomal barriers imposed by histone proteins. Among the well-known covalent modifications of histones, the reversible acetylation of internal lysine residues in histone amino-terminal domains has long been positively linked to ...
S Y, Roth, J M, Denu, C D, Allis
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▪ Abstract Transcriptional regulation in eukaryotes occurs within a chromatin setting and is strongly influenced by nucleosomal barriers imposed by histone proteins. Among the well-known covalent modifications of histones, the reversible acetylation of internal lysine residues in histone amino-terminal domains has long been positively linked to ...
S Y, Roth, J M, Denu, C D, Allis
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BioEssays, 1985
AbstractHistones occur in equal amounts to DNA in the cell nucleus and are largely responsible for the compaction of the genome into chromatin via the formation of nucleosomes and higher‐order structures. Whereas two of the five histone types exhibit little structural variation, the remaining three occur in many variant tissue‐ or species‐specific ...
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AbstractHistones occur in equal amounts to DNA in the cell nucleus and are largely responsible for the compaction of the genome into chromatin via the formation of nucleosomes and higher‐order structures. Whereas two of the five histone types exhibit little structural variation, the remaining three occur in many variant tissue‐ or species‐specific ...
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2008
Deacetylation of histones is required for gene regulation and cell cycle progression and the mediators, the histone deacetylases, are being vigorously pursued as drug targets for cancer chemotherapy. The deacetylases are also potential drug targets against infectious diseases and genome sequencing revealed proteins of this class in each of three ...
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Deacetylation of histones is required for gene regulation and cell cycle progression and the mediators, the histone deacetylases, are being vigorously pursued as drug targets for cancer chemotherapy. The deacetylases are also potential drug targets against infectious diseases and genome sequencing revealed proteins of this class in each of three ...
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[Histone variants and histone exchange].
Yi chuan = Hereditas, 2009Histones, as the basic components of nucleosome, are essential to chromatin structure and function. To adapt to various states of chromatin, corresponding histone variants are incorporated in nucleosome, and certain modifications also occur on the variants' tails.
Nan, Wu, Jian-Fang, Gui
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