Results 281 to 290 of about 245,589 (335)

Lytic or Latent Phase in Human Cytomegalovirus Infection: An Epigenetic Trigger. [PDF]

Int J Mol Sci
Cevenini A, De Antonellis P, Mazzarelli LL, Sarno L, D'Alessandro P, Pellicano M, Salomè S, Raimondi F, Guida M, Maruotti GM, Miceli M.   +10 more
europepmc   +1 more source

Acetate promotes T cell effector function during glucose restriction [PDF]

, 2019
Egawa, Takeshi, et al,, Maggi, Leonard B, Jr.   +2 more
core   +1 more source

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

Advanced Science, EarlyView.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu, Le Xie, Yuan Jin, Sen Chen, Xinyu Shi, Yanjun Zong, Zhengdong Zhao, Wei‐Jia Kong, Yu Sun   +8 more
wiley   +1 more source

Catalytic IgG Antibodies Hydrolyze DNA, Histones, and HMGB1 in Systemic Lupus Erythematosus. [PDF]

Int J Mol Sci
Melamud MM, Ermakov EA, Tolmacheva AS, Kostrikina IA, Sizikov AE, Nevinsky GA, Buneva VN.   +6 more
europepmc   +1 more source

Histon [PDF]

, 2018
openaire   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Advanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo   +9 more
wiley   +1 more source

Chromatin relaxation dynamics and histone PTMs in the early DNA damage response. [PDF]

Cancer Biol Med
Qian J, Xie Z, Zhou L, Zhu WG.
europepmc   +1 more source

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

Advanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang, Wanyou Feng, Yanyan Yang, Yu Pan, Chaoxia Zou, Leyi Wang, Sanbao Zhang, Yimin Zhao, Yongmei Wu, Jinling Wang, Jianwei Zou, Kehe Cen, Yongwang Zhang, Han Huang, Yurong Xu, Li Zhong, Hailong Gong, Juanru Cheng, Jingyuan Liang, Zihua Zheng, Qinyang Jiang, Jingwei Wei, Hui Li, Minhui Liang, Deshun Shi, Sufang Yang, Yanfei Deng, Yingming Wei   +27 more
wiley   +1 more source

Exploring KAT6 as a therapeutic target in breast cancer: epigenetic approaches for precision medicine. [PDF]

NPJ Breast Cancer
Roussel-Simonin C, Fernandez-Martinez A, Postel-Vinay S, Mosele F, Viansone A, Massard C, Mouren A, Vibert J, Pistilli B.   +8 more
europepmc   +1 more source

Histone [PDF]

, 2019
openaire   +1 more source