Results 131 to 140 of about 1,368,556 (344)

Caddoan Ceremonial Sites of the Caddoan Cultural Area of Arkansas, Louisiana, Oklahoma, and Texas: Draft Caddo National Landmark Nomination [PDF]

open access: yes, 1999
Since 1997, we have been working on the development of a National Historic Landmark (NHL) cover nomination for Caddoan ceremonial sites - earthen mounds in the Caddoan cultural area of southwestern Arkansas, northwestern Louisiana, eastern Oklahoma, and ...
Barnes, Mark R., Perttula, Timothy K.
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Historic Cities Project Task 4 – The Business Surveys: Questionnaire Design, Implementation and Initial Analysis. [PDF]

open access: yes, 2005
The Historic Cities project examined the potential impacts of transport demand management strategies on three case study ‘historic’ cities in England. These cities are York, Cambridge and Norwich, all of which have the following characteristics: - they ...
Jopson, A., Still, B.
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Supernova SN 1006 in two historic Yemeni reports

open access: yes, 2015
We present two Arabic texts of historic observations of supernova SN 1006 from Yemen as reported by al-Yamani and Ibn al-Dayba (14th to 16th century AD).
Neuhaeuser, Ralph, Rada, Wafiq
core   +1 more source

HISTORICAL [PDF]

open access: yesBritish Journal of Ophthalmology, 1946
openaire   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Historic Preservation Program newsletter [PDF]

open access: yes, 2008
2014. UVM Historic Preservation Program newsletter.https://scholarworks.uvm.edu/hpnewsletter/1001/thumbnail ...
University of Vermont. Historic Preservation Program.
core   +8 more sources

Home - About - Disclaimer - Privacy