Results 131 to 140 of about 1,389,299 (344)
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
, 2013 Abstract Marx’s theory of history is often misrepresented as a mechanically deterministic and fatalistic theory of change in which the complexity of the real world is reduced to simple, unconvincing abstractions. Nothing could be further from the truth.
openaire +2 more sources
Paradise Lost Revisited: GM and the UAW in Historical Perspective [PDF]
, 2010 Purpose Analysis of historic relationship between GM and Union of Automobile Workers (UAW) from 1936 through the moment of bankruptcy of GM in 2009.
de Gier, Erik
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Plant gum identification in historic artworks [PDF]
, 2017 Clara Granzotto +3 more
openalex +1 more source
Utilization of Historic Information in an Optimisation Task [PDF]
, 1984 One of the basic components of a discrete model of motor behavior and decision making, which describes tracking and supervisory control in unitary terms, is assumed to be a filtering mechanism which is tied to the representational principles of human ...
Boesser, T.
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
The Twenty-Fifth Amendment to the United States Constitution: A Reader\u27s Guide [PDF]
, 2018 Historic overview and analysis of presidential succession coupled with findings of the law ...
Yale Law School Rule of Law Clinic
core +1 more source