Results 131 to 140 of about 1,341,883 (294)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Legacy and Springboard: The Untapped Potential of Archaeological Archives for Scientific Innovation
Internet ArchaeologyArchaeological archives form a public resource that enables the reinterpretation of original findings from archaeological investigations, provides the raw material for further research, informs museum displays and teaching collections, and gives society ...
Barney Sloane
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Caddoan Ceremonial Sites of the Caddoan Cultural Area of Arkansas, Louisiana, Oklahoma, and Texas: Draft Caddo National Landmark Nomination [PDF]
, 1999 Since 1997, we have been working on the development of a National Historic Landmark (NHL) cover nomination for Caddoan ceremonial sites - earthen mounds in the Caddoan cultural area of southwestern Arkansas, northwestern Louisiana, eastern Oklahoma, and ...
Barnes, Mark R., Perttula, Timothy K.
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
How Best to Educate the Next Generation in Historic Preservation [PDF]
, 2012 Ten key takeaways from a first-of-its-kind conference on preservation education, hosted by the School of Architecture, Art and Historic ...
Clark, Brian E.
core +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Nature, Place, and Story: Rethinking Historic Sites in Canada by Claire Campbell [PDF]
, 2018 Review of Claire Campbell\u27s Nature, Place, and Story: Rethinking Historic Sites in ...
Morgan-Thorp, Emma K
core +1 more source