Results 71 to 80 of about 7,049,835 (311)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Underground fieldwork - A cultural and social history of cave cartography and surveying instruments in the 19th and at the beginning of the 20th century

, 2015
At the turn of the 20th century, the practical examination of caves went through a radical change. Governmental organizations and private clubs were founded in an attempt to establish speleology as an independent academic subject.
Mattes, Johannes (Department of History, Faculty of Historical and Cultural Studies, University of Vienna)
core   +1 more source

Shapes of Clay Vessels As a Subject of Study. Historical-and-Cultural Approach.

ФОРМЫ ГЛИНЯНЫХ СОСУДОВ КАК ОБЪЕКТ ИЗУЧЕНИЯ, 2018
Сборник состоит из двух частей. Первая часть содержит статьи выдающегося советского и российского археолога-керамиста А.А. Бобринского, посвященные методам изучения форм глиняных сосудов и изданные в 1986–1999 гг., а также неопубликованную статью 1984 г.
openaire   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Time frames. Negotiating Cultural History

, 2015
Time Frames brings together a group of cultural historians studying several different periods and locations in the history of Western culture, to discuss the temporal structures which historical studies live by.
Tuohela, Kirsi (toim.), Korhonen, Anu
core  

Knowledge-based model for geomaterials in the Ancient Centre of Naples (Italy): towards an integrated approach to cultural heritage

, 2020
An integrate approach, aimed at allowing the access to a large dataset, concerning Cultural Heritage, is proposed. The research, developed within Databenc-SNECS (High-Tech District for Cultural Heritage – Social Network of Historic Center Entities ...
Morra V., Allocca V., De Vita P., Calcaterra D., Guarino V., Di Benedetto C., Gautiero A., Cappelletti P.   +7 more
core   +1 more source

Chinese legal-philosophic syncretism and its influence to value orientations of the Chinese society

Cхід, 2019
The article is devoted to researching of historical-cultural and legal-philosophic factors that influence on the formation of value orientations inside the Chinese society.
Oleksandr Stovpets
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Conceiving Concepts and Conceptions: A Cultural-Historical Approach

, 2011
A science that does not critically interrogate its theoretical concepts literally does not know what it is doing. The attempt to clarify a widely used concept in psychological research-the concept of concept-therefore constitutes an important effort in ...
Wolff-Michael Roth, Roth, Wolff-Michael
core   +1 more source

Active Teaching Approach: Teaching and Learning Methods on Historical and Cultural Theory

Creative Education, 2014
This study is a theoretical synthesis of researches performed in the scholar context aiming to present an active teaching and learning proposal that sees teaching approach as the dialectical unity in concepts of internalization movement. The actions are organized by the professor and carried out by the subjects who are actively involved in the ...
openaire   +2 more sources