Results 121 to 130 of about 1,898,566 (310)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
History Begins in the Future: On Historical Sensibility in the Age of Technology [PDF]
, 2018 The humanities and the social sciences have been hostile to future visions in the postwar period. The most famous victim of their hostility was the enterprise of classical philosophy of history, condemned to illegitimacy precisely because of its ...
Simon, Zoltán Boldizsár
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XVIIIe congrès international des sciences historiques [PDF]
, 2020 La Société historique du Canada sera l'hôte en 1995 du XVIIIe congrès international des sciences historiques. Le Comité international des sciences historiques (CISH) / International Committee of Historical Sciences, dont les bureaux administratifs se ...
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Economics, Biology, and Culture: Hodgson on History [PDF]
, 2003 This book addresses what the author claims, with considerable justification, to be the foremost challenge confronting the social and behavioral sciences today: the problem of historical specificity.
Field, Alexander J.
core +1 more source
Transversal: International Journal for the Historiography of Science, 2018 Book Review:Condé, Mauro L. “Um Papel para a História”: O Problema da Historicidade da Ciência. [“A role for the History”: The Problem of the Historicity of Science].
openaire +3 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Foundation Funding for the Humanities: An Overview of Current and Historical Trends [PDF]
, 2004 Foundation Funding for the Humanities: An Overview of Current and Historical Trends, finds that funding for fields such as art history, history and archeology, languages and linguistics, area studies, and the humanistic social sciences increased two and ...
Loren Renz, Steven Lawrence
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source