Results 121 to 130 of about 353,625 (313)

MEDIEVAL SILK TEXTILE FROM THE NORTHWESTERN CASPIAN AND THE LOWER DON REGIONS: TECHNOLOGICAL ANALYSIS, 14С DATA, THE 15N AND 13C ISOTOPIC COMPOSITION OF ANCIENT CLOTHS

open access: yesНижневолжский археологический вестник
Textile is a unique source of information on technology and production stages from raw material cultivation to fabric manufacture, as well as on the people who produced the raw material, spun it into threads, and wove it into cloth; sewed garments ...
Natalia Shishlina   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Průmysl sociálního vyloučení: Lokalita Janov

open access: yesAntropoWebzin, 2010
The article argues that we should study social exclusion not only in one particular locality, but rather through a multi-sited approach, which would take into account the various sites of the directing system (in governmental and non-governmental ...
Michal Tošner   +5 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

International Bibliography of Historical Sciences, 8e année, 1933 [PDF]

open access: yes, 1936
Cahen Léon. International Bibliography of Historical Sciences, 8e année, 1933. In: Revue d'histoire moderne, tome 11 N°22,1936. pp.
Cahen, Léon
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Science and its Historicity

open access: yesTransversal: International Journal for the Historiography of Science, 2018
Book Review:Condé, Mauro L. “Um Papel para a História”: O Problema da Historicidade da Ciência. [“A role for the History”: The Problem of the Historicity of Science].
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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