Results 131 to 140 of about 1,898,566 (310)
A happy historian with a museum past: on the 65th anniversary of Mikhail Igorevich Rodnov
Из истории и культуры народов Среднего ПоволжьяThe essay briefly examines the scientific biography of Doctor of Historical Sciences, leading researcher at the Institute of History, Language and Literature of the Ufa Federal Research Center of the Russian Academy of Sciences M.I. Rodnov.
Mikhail Vladimirovich Gaukhman
doaj +1 more source
Privacy and Confidentiality Issues in Historical Health Sciences Collections [PDF]
, 2012 Historical health sciences collections are rare and unique materials containing large amounts of information subject to confidentiality and privacy laws and concerns.
Gilliland, Anne T., Wiener, Judith A.
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Webmapping in the historical and archaeological sciences. An introduction [PDF]
, 2008 The paper introduces the concept of webmapping in the archaeological and historical sciences. The interest in offering an online mapping service is developed in terms of collaborative working, technical support, e-learning, mapping functions, and ...
Djindjian, F.
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Documenta PraehistoricaIn this paper we address the biography of a set of copper nails recovered in 1998 from a Late Iron Age structure located at the archaeological site of Puig de Sa Morisca (Mallorca, Spain).
Laura Perelló Mateo +4 more
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Fractional Calculus in Wave Propagation Problems [PDF]
, 2012 Fractional calculus, in allowing integrals and derivatives of any positive order (the term "fractional" kept only for historical reasons), can be considered a branch of mathematical physics which mainly deals with integro-differential equations, where ...
Mainardi, Francesco
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Role of Scientific Discovery in the Establishment of the First Biological Weapons Programmes [PDF]
, 2005 YesThis report addresses the scientific and technological discoveries in the biological sciences that enabled the early interest in biological warfare to move from hurling infected corpses into enemy cities in ancient times, through use of small cultures
Davison, N.
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source