Results 91 to 100 of about 432,891 (284)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

FOUNDATION OF INSTITUTIONAL FORMS OF ARTISAN TRAINING IN THE URAL REGION IN THE XVII–XVIII CENTURIES

Образование и наука, 2015
The research objective is to demonstrate the specificity of artisan training in the Ural region in the XVII–XVIII centuries, and explore the relating historical and pedagogical heritage and its implementation in the modern vocational training system ...
Andrey V. Moiseev, Andrey V. Yefanov
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Sense-specific Historical Word Usage Generation

Transactions of the Association for Computational Linguistics
Abstract Large-scale sense-annotated corpora are important for a range of tasks but are hard to come by. Dictionaries that record and describe the vocabulary of a language often offer a small set of real-world example sentences for each sense of a word.
Pierluigi Cassotti, Nina Tahmasebi
openaire   +1 more source

Heideggerian Marxism [PDF]

, 2009
An extended review of the English collection of Marcuse's essays and interviews on Heidegger that addresses the philosophical basis of a synthesis of Marx and ...
Angus, Ian
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Information Technology and Information Approach in Historical Research

RUDN Journal of Russian History, 2011
The article is devoted to the evolution of theoretical and applied aspects of information technology in historical research. The author shows that the development of theoretical concepts of an information approach, methodological and technological ...
I M Garskova
doaj  

Formulating and evaluating time series algorithms to forecast daily asthma hospital admissions

Journal of Clinical and Translational Science
Introduction: Asthma exacerbations are frequent causes of pediatric hospital admissions. We sought to develop a time series algorithm to forecast next-day daily asthma hospitalizations.
Stephen P. Colegate, Michael Seid, David Hartley, Aaron Flicker, Joseph Bruce, Joseph Michael, Mfonobong Udoko, Andrew F. Beck, Cole Brokamp   +8 more
doaj   +1 more source

ETHICS AND BASIC PRINCIPLES OF RESTORING HISTORICAL STONE MONUMENTS

Ochrona Dziedzictwa Kulturowego, 2019
The paper discusses ethical guidelines in relation to the conservation of historical monuments made of stone. The presented rules consider the building stone specificity and its susceptibility to various corrosion factors and the character of ...
Jadwiga W. Łukaszewicz
doaj   +1 more source

Transcriptome analysis of Azospirillum lipoferum during its interaction with rice [PDF]

, 2012
The associative symbiosis between Plant Growth Promoting Rhizobacteria of the genus Azospirillum and cereals have mainly been studied from an agronomic and economic point of view, and several studies showed that plant morphological and metabolic changes ...
Borland, Stéphanie, Drogue, Benoit, Prigent-Combaret, Claire, Sanguin, Hervé, Wisniewski-Dyé, Florence   +4 more
core