Results 121 to 130 of about 1,357,671 (290)
A coral reef as an analogical model to promote collaborative learning on cultural and ethnic diversity in science [PDF]
An exercise designed to engage students in critical thinking and active conversation about gender, diversity, and ethnicity in science is described.
Gonzalez, Edward L. F., Yost, Robert W.
core
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
THE OPERATIONAL COMPONENT AND THE FORMATION OF A HISTORICAL CULTURE [PDF]
The formation of a historical culture is a process by which the conscious appropriation of a conception allows to operate in the cognitive, attitudinal and evaluative areas is produced, illustrating in its context ...
Lainy Rodríguez Hurtado +2 more
doaj
Complexity and Philosophy [PDF]
The science of complexity is based on a new way of thinking that stands in sharp contrast to the philosophy underlying Newtonian science, which is based on reductionism, determinism, and objective knowledge.
Cilliers, Paul +2 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Book review: austerity: the great failure by Florian Schui [PDF]
Adopting a historical approach, Florian Schui provides an insightful and thought provoking narrative on the concept of austerity, finds Lee Gregory.
Gregory, Lee
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Students’ views of historical significance – a narrative literature review
This narrative literature review describes and critically discusses 21 years of international research addressing students’ views of historical significance. The data consist of 32 educational research articles published between 2000 and 2021. The review
doaj +2 more sources
Ways of Saying, Ways of Seeing. Public Images of Teachers (19th-20th Centuries) [PDF]
The article is organized into three main sections: In the first section, inspired by the work of Martin Jay, I try to show the denigration of vision in historical thinking, suggesting that images are demanding new theoretical and methodological ...
Novoa, Antonio
core

