Results 121 to 130 of about 1,357,671 (290)

A coral reef as an analogical model to promote collaborative learning on cultural and ethnic diversity in science [PDF]

open access: yes, 2008
An exercise designed to engage students in critical thinking and active conversation about gender, diversity, and ethnicity in science is described.
Gonzalez, Edward L. F., Yost, Robert W.
core  

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

THE OPERATIONAL COMPONENT AND THE FORMATION OF A HISTORICAL CULTURE [PDF]

open access: yesVarela, 2018
The formation of a historical culture is a process by which the conscious appropriation of a conception allows to operate in the cognitive, attitudinal and evaluative areas is produced, illustrating in its context ...
Lainy Rodríguez Hurtado   +2 more
doaj  

Complexity and Philosophy [PDF]

open access: yes, 2006
The science of complexity is based on a new way of thinking that stands in sharp contrast to the philosophy underlying Newtonian science, which is based on reductionism, determinism, and objective knowledge.
Cilliers, Paul   +2 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Book review: austerity: the great failure by Florian Schui [PDF]

open access: yes, 2015
Adopting a historical approach, Florian Schui provides an insightful and thought provoking narrative on the concept of austerity, finds Lee Gregory.
Gregory, Lee
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Students’ views of historical significance – a narrative literature review

open access: yesHistory Education Research Journal
This narrative literature review describes and critically discusses 21 years of international research addressing students’ views of historical significance. The data consist of 32 educational research articles published between 2000 and 2021. The review
doaj   +2 more sources

Ways of Saying, Ways of Seeing. Public Images of Teachers (19th-20th Centuries) [PDF]

open access: yes, 2000
The article is organized into three main sections: In the first section, inspired by the work of Martin Jay, I try to show the denigration of vision in historical thinking, suggesting that images are demanding new theoretical and methodological ...
Novoa, Antonio
core  

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