Results 111 to 120 of about 100,216 (309)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Episode 5: Historical Thinking

, 2021
In this episode, we take a deeper look at the definitions and five standards for historical thinking in the elementary social studies classroom. What does it mean for young learners and teachers to think like a historian?https://dc.etsu.edu/social ...
Meier, Lori T.
core  

Students’ use and perception of history textbooks in Grades 9 to 13: a retrospective study revealing general insights and latent profiles

History Education Research Journal
This quantitative study reveals the usage of history textbooks in upper secondary school settings in comparison with already published data taken from lower secondary school settings.
doaj   +2 more sources

Digital Infrastructure for Art Historical Research: thinking about user needs [PDF]

, 2012
Christina Kamposiori
openalex   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

What If I Were the Exile? Linking Past and Present for Democratic History Teaching with Pre-Service Educators

Education Sciences
The academic literature has fostered a debate in recent decades regarding the concept of historical empathy and the typology of activities that can help to treat and develop it, although there is no consensus as to the real effectiveness of narrative ...
María Belén San Pedro Veledo, María Luisa Zagalaz-Sánchez, Carmen González González de Mesa   +2 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Historical Thinking in Ontario Secondary Schools: A Multiple Case Study

, 2022
In recent decades, history and education scholars in the Western world have argued for a constructivist approach to disciplinary thinking in history, known as historical thinking.
Bussell, David Andrew
core  

Pengaruh Penggunaan Media Pembelajaran Wordwall untuk Meningkatkan Minat Belajar dan Berpikir Sejarah Peserta Didik di SMA Negeri 7 Bandung

Fajar Historia: Jurnal Ilmu Sejarah dan Pendidikan
History learning is one of the subjects that students are less interested in because it discusses space and time in the past. With the lack of interest in learning history affects the historical thinking of students which can be seen from the low ...
Thalia Natasya Syarief, Tarunasena Tarunasena, Yeni Kurniawati   +2 more
doaj   +1 more source