Results 111 to 120 of about 1,367,711 (304)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Historiology: Outline of a theory of historiology
Memoria y Civilización, 2012 The article analyzes historical thinking and emphasizes its specific form of historical studies. It explicates historical thinking as a mental and spiritual process of making sense of time by referring to the experience of the past.
Jörn Rüsen
doaj
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Using ideas derived from historical institutionalism to illuminate the long-term impacts on crime of ‘Thatcherite’ social and economic policies [PDF]
, 2014 In this working paper, we outline our thinking on a very large and complex undertaking; namely the assessment of the ways in which the Thatcher governments of the 1980s may have had quite unintended consequences on crime via some of the policies which ...
Farrall, S. +3 more
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Education SciencesThe academic literature has fostered a debate in recent decades regarding the concept of historical empathy and the typology of activities that can help to treat and develop it, although there is no consensus as to the real effectiveness of narrative ...
María Belén San Pedro Veledo +2 more
doaj +1 more source
Some Relevant Econophysics’ Moments of History, Definitions, Methods, Models and New Trends [PDF]
New models result from a new way of thinking or from the trans-disciplinary methods used in new domains. Econophysics improve the quality of the classical research of Economics through its original models and methods.
Gheorghe Săvoiu, Ion Iorga–Simăn
core
The question concerning the environment: a Heideggerian approach to environmental philosophy : a thesis presented in partial fulfillment of the requirements for the degree of Master of Arts in Philosophy at Massey University [PDF]
, 2008 This thesis will engage with the thinking of Martin Heidegger in order to show that our environmental problems are the necessary consequences of our way of 'knowing' the world.
Bowyer, Lynne
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Fajar Historia: Jurnal Ilmu Sejarah dan PendidikanHistory learning is one of the subjects that students are less interested in because it discusses space and time in the past. With the lack of interest in learning history affects the historical thinking of students which can be seen from the low ...
Thalia Natasya Syarief +2 more
doaj +1 more source