Results 121 to 130 of about 100,216 (309)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

THE OPERATIONAL COMPONENT AND THE FORMATION OF A HISTORICAL CULTURE [PDF]

open access: yesVarela, 2018
The formation of a historical culture is a process by which the conscious appropriation of a conception allows to operate in the cognitive, attitudinal and evaluative areas is produced, illustrating in its context ...
Lainy Rodríguez Hurtado   +2 more
doaj  

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Approaches to teaching Aboriginal history and politics

open access: yes, 2019
Rich with insights into historical skills, historical concepts and critical thinking, as well as practical guidance on translating principles into engaging classroom approaches, this is an essential reference for both pre-service and in ..
Norman, H
core  

HISTORICAL THINKING AND NATIONAL CULTURAL HERITAGE

open access: yes, 2018
The article reflects the importance of the rich cultural heritage created by our people in the formation of historical thinking, the special place of the historical thinking that has passed through time and reached us, the importance of its preservation ...
Karimov, Y
core   +2 more sources

Students’ views of historical significance – a narrative literature review

open access: yesHistory Education Research Journal
This narrative literature review describes and critically discusses 21 years of international research addressing students’ views of historical significance. The data consist of 32 educational research articles published between 2000 and 2021. The review
doaj   +2 more sources

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Examining Children’s Historical Thinking in Hands-On History Spaces

open access: yes, 2017
Thesis (Master's)--University of Washington, 2017-06To combat the spread of fake news, researchers and academics point to historical thinking as a possible solution.
Martinko, Megan Alexandra
core  

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