Results 91 to 100 of about 100,216 (309)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Fostering Historical Empathy: Empowering Students in Online Teaching

open access: yes, 2023
Learning history goes beyond rote memorization of facts; it is an engaging exploration of the past, cultivating critical thinking and fostering engaged citizenship.
Duan, Lei
core  

A competence-based test to assess historical thinking in secondary education: Design, application, and validation [PDF]

open access: diamond, 2021
Jesús Domínguez-Castillo   +5 more
openalex   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Enseñanza de la historia e inclusión educativa: la experiencia de tener dos alumnos ciegos en mi aula

open access: yesClio y Asociados, 2017
This article deals with the relevance of teaching history as a promoter of the educational inclusion of two blind students in a regular secondary school. It was based on the idea that the current school curriculum tends towards exclusion,
Mayra Rodríguez Hernández
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Historical Thinking Online

open access: yes, 2018
This thesis explored the impact of digital learning settings, and their associated social practices, on an individual’s historical thinking (Wineburg, 1991).
Goulding, James Charles
core  

Podcasts as Teacher Talk in Historical Thinking

open access: yesHistorical Encounters: A Journal of Historical Consciousness, Historical Cultures, and History Education
One of the challenges associated with preparing teacher-candidates to teach historical thinking involves moving away from narrative practices that inhibit explicit use of historical thinking concepts.
Cynthia Wallace-Casey
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Beyond the Individual Cognitive Perspective: A Framework for Inclusive History Education

open access: yesPanta rei
Although inclusion is becoming increasingly important in history education, a theory specifically geared towards inclusive historical thinking and learning is still missing.
Sebastian Barsch   +2 more
doaj   +1 more source

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