Results 111 to 120 of about 6,995,982 (396)

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

Indonesian Higher Education: The Chronicle, Recent Development and The New Legal Entity Universities [PDF]

open access: yes
This paper reviews and presents the concise history of higher education Indonesia from pra-colonial period to the latest era when the Government of Republic Indonesia proposed the Educational Legal Entity Bill and the Law on National Education System ...
Mohamad Fahmi
core  

Reflections on becoming a teacher and the challenges of teacher education [PDF]

open access: yes, 2011
In this lecture, the context and conditions of becoming a teacher from the time of being selected into the programme, through the process of training and being retained to teach are discussed within the framework of Teacher Education in Nigeria.
Afe, John O.
core  

Reassessing 1960s philosophy of the curriculum [PDF]

open access: yes, 2005
A prominent thesis of British philosophy of education in the 1960s was that the pursuit of different forms of knowledge is central to education. The fact that the thesis is difficult to justify philosophically raises questions about its historical ...
White, John
core   +3 more sources

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Updating the art history curriculum: incorporating virtual and augmented reality technologies to improve interactivity and engagement [PDF]

open access: yes, 2017
Master's Project (M.Ed.) University of Alaska Fairbanks, 2017This project investigates how the art history curricula in higher education can borrow from and incorporate emerging technologies currently being used in art museums. Many art museums are using
Bender, Brook
core  

ISLAMIC EDUCATION INTITUTIONS IN THE CLASSICAL PERIOD (UMAYYAD AND ABBASID PERIODS) [PDF]

open access: yes
Islamic education has existed since the Prophet Muhammad SAW and continues to develop until now. Islam once reached the peak of glory, called the golden age, because, at that time, Islamic education was very developed and produced an extraordinary ...
Faridi, Faridi   +2 more
core   +1 more source

Exploring supplementary education: margins, theories and methods. [PDF]

open access: yes, 2011
Existing knowledge of supplementary education, that is education organised and run by political, faith or ethnic groups outside of formal schooling, is patchy.
Grosvenor, Ian, Myers, Kevin
core   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

open access: yesMolecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda   +3 more
wiley   +1 more source

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