Results 81 to 90 of about 6,995,982 (396)

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Education vs. Entertainment: A Cultural History of Children's Software [PDF]

open access: yes, 2007
Part of the Volume on the Ecology of Games: Connecting Youth, Games, and Learning This chapter draws on ethnographic material to consider the cultural politics and recent history of children's software and reflects on how this past can inform our current
Mizuko Ito
core  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Development of Evernoted Learning Media Center as Learning Innovation and Assistive Technology for People with Disabilities

open access: yesJurnal Teknologi Pendidikan
The development of Evernoted Learning Media Center aims to introduce inclusive learning innovations for people with disabilities. This study presents the design and implementation of an Evernoted-based learning platform with accessibility features ...
Riski Agung Novarianto   +6 more
doaj   +1 more source

Tabib Family’s Role on Fracture Treatment in Aceh, 1950-2020: A Historical Reconstruction

open access: yesIHiS (Indonesian Historical Studies), 2020
This research traces the origin of traditional fracture treatment, and identifies the values of local wisdom, especially in traditional healing process performed by the tabib family and to describe how the traditional healing system is developed from ...
Teuku Kusnafizal   +2 more
doaj   +1 more source

[Review of] Margaret Connell Szasz. Indian Education in the American Colonies, 1607-1783 [PDF]

open access: yes, 1991
In this ethnohistory of American Indian education, Margaret Szasz broadly interprets education to mean the transmission of culture over time. Within the arena of contact, prominent Indians who helped mediate the relations between Euro -- and Native ...
Harvey, Gretchen
core   +1 more source

‘Walking in a Foreign and Unknown Landscape’ : studying the history of mathematics in initial teacher education [PDF]

open access: yes, 2013
This article develops the argument that students in initial teacher education benefit in terms of who they are becoming from developing awareness of and engagement in the history of mathematics.
Povey, Hilary
core   +1 more source

Educational multi-touch applications, number sense, and the homogenizing role of the educator [PDF]

open access: yesarXiv, 2016
As part of an educational project proposed in Italian preschools, an educator followed a tested protocol proposing two chosen iPad apps to children of ages 5 to 6. Though her interventions were supposedly aimed at strengthening the number sense of the children, the result was a homogenization of their schemes, in various cases seemingly inhibiting ...
arxiv  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy